246868-65-5Relevant academic research and scientific papers
The application of vinylogous iminium salt derivatives to an efficient relay synthesis of the pyrrole containing alkaloids polycitone A and B
Gupton, John T.,Miller, Robert B.,Krumpe, Keith E.,Clough, Stuart C.,Banner, Edith J.,Kanters, Rene P.F.,Du, Karen X.,Keertikar, Kartik M.,Lauerman, Nicholas E.,Solano, John M.,Adams, Bret R.,Callahan, Daniel W.,Little, Barrett A.,Scharf, Austin B.,Sikorski, James A.
, p. 1845 - 1854 (2007/10/03)
A new and efficient relay synthesis of the marine natural products polycitone A and B is described. The new strategy relies on the formation of 2,4-disubstituted pyrroles from a vinamidinium salt followed by electrophilic substitution at the 5-position of
The cytotoxicity and mode of action of 2,3,4-trisubstituted pyrroles and related derivatives in human Tmolt4 leukemia cells
Gupton,Burham,Byrd,Krumpe,Stokes,Shuford,Winkle,Webb,Warren,Barnes,Henry,Hall
, p. 691 - 697 (2007/10/03)
4-Carbethoxy-1-methyl-2-phenacyl-3-phenylpyrrole (9), 4-carbethoxy-2-(4- methoxybenzoyl)-3-(4-methoxyphenyl)pyrrole (10) and 2-(4-methoxybenzoyl)-3,4- bis-(4-methoxyphenyl)pyrrole (11) proved to be potent cytotoxic agents against the growth of murine and
