246869-14-7

Basic information

• Product Name: ethoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester
• CAS NO: 246869-14-7
• Molecular Weight: 328.386
• Mol File: 246869-14-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ethoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester(246869-14-7)
• EPA Substance Registry System: ethoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester(246869-14-7)

Safety Data

• Hazardous Substances Data: 246869-14-7(Hazardous Substances Data)

Upstream product

• 71867-98-6 2-hydroxy-2-methyl-1-(4-(methylthio)phenyl)-propan-1-one 
• 53207-58-2 2-methyl-1-(4-(methylthio)phenyl)-propan-1-one 
• 100-68-5 methyl-phenyl-thioether 
• 627-03-2 3-oxapentanoic acid 
• 180048-73-1 2-hydroxy-2-methyl-1-(4-(methylsulfonyl)-phenyl)propan-1-one 

Relevant articles and documents

SAR in the alkoxy lactone series: The discovery of DFP, a potent and orally active COX-2 inhibitor

Extensive SAR has been established in the alkoxy lactone series and this has lead to the discovery of DFP (5,5-dimethyl-3-(2-propoxy)-4- methanesulfonylphenyl)-2(5H)-furanone), a potent COX-2 inhibitor exhibiting in vivo efficacy in all models studied.