71867-98-6

Basic information

• Product Name: 1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]-
• CAS NO: 71867-98-6
• Molecular Formula: C11H14O2S
• Molecular Weight: 210.297
• Mol File: 71867-98-6.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]-(71867-98-6)
• EPA Substance Registry System: 1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]-(71867-98-6)

Safety Data

• Hazardous Substances Data: 71867-98-6(Hazardous Substances Data)

Usage

General Description

1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]-, known as 4-Methylthiophenyl-2-butanone or p-Methylthio-α-methyl phenylacetone, is an organic compound with the chemical formula C12H16OS. It is a pale yellow liquid with a sweet, floral odor. 1-Propanone, 2-hydroxy-2-methyl-1-[4-(methylthio)phenyl]- is commonly used in the synthesis of various pharmaceuticals and chemical intermediates. It is also known for its role in the production of illegal drugs like methamphetamine. Due to its potential for abuse, 4-Methylthiophenyl-2-butanone is a controlled substance in many countries. Additionally, it is considered a hazardous material and should be handled with caution.

Upstream product

• 71867-96-4 1-(4-chlorophenyl)-2-hydroxy-2-methylpropan-1-one 
• 5188-07-8 sodium thiomethoxide 
• 88324-55-4 2-bromo-2-methyl-1-[4-(methylsulfanyl)phenyl]propan-1-one 
• 162012-21-7 2-trimethylsilyloxy-4'-(methylthio)isobutyrophenone 
• 100-68-5 methyl-phenyl-thioether 
• 53207-58-2 2-methyl-1-(4-(methylthio)phenyl)-propan-1-one 

Downstream Products

• 180048-73-1 2-hydroxy-2-methyl-1-(4-(methylsulfonyl)-phenyl)propan-1-one 
• 162012-22-8 2-(4-fluorophenylacetoxy)-4'-(methylthio)isobutyrophenone 
• 189955-80-4 cyclohexyloxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 246869-09-0 cyclopentyloxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 190966-56-4 (1-cyclopropyl-ethoxy)-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 246869-15-8 2-cyclopropylmethoxyacetic acid [1,1-dimethyl-2-(4-methanesulfonylphenyl)-2-oxoethyl]ester 
• 246869-10-3 cyclobutoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 189955-92-8 (1-ethyl-propoxy)-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 189954-96-9 3-(Cyclopropylmethoxy)-5.5-dimethyl-4-(4-(methylsulfonyl)phenyl)-5H-furan-2-one 
• 246869-11-4 cyclopropoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 246869-12-5 sec-butoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 
• 190966-51-9 isopropoxy-acetic acid 2-(4-methanesulfonyl-phenyl)-1,1-dimethyl-2-oxo-ethyl ester 

Relevant articles and documents

Monosubstituted and polysubstituted functional group aromatic ketone compounds, and preparation method and photopolymerization initiator thereof

The invention belongs to the field of radiation curing new materials, and relates to an aromatic ketone compound, in particular to a monosubstituted or polysubstituted polyfunctional group aromatic ketone compound, a preparation method thereof and a photopolymerization composition containing an ethylenically unsaturated compound system, which takes the compound as an effective component. The invention provides monosubstituted and polysubstituted polyfunctional group aromatic ketone compounds. The polyfunctional group aromatic ketone compounds have a general formula structure as shown in (I). The invention also discloses a preparation method and an application of the polyfunctional aromatic ketone compound. According to the invention, industrial-grade raw materials which are low in cost and easy to obtain are used as a starting point to prepare the monosubstituted or polysubstituted functionalized aromatic ketone compound in a breakthrough way, and the compound is applied to a photoinitiator in radiation curing, so that the problems of toxicity and VOCs pollution of the photoinitiator are solved, and the economic competitiveness of the photoinitiator is strived; the overall cost is reduced, and the photo-initiation efficiency is improved.

PROCESS FOR THE PREPARATION OF ALPHA-FUNCTIONALIZED KETONES

The present invention refers to a process for the preparation of an α-functionalized ketone, an α-functionalized ketone obtained by said process, a photopolymerizable composition comprising the α-functionalized ketone and at least one photopolymerizable unsaturated compound, a method of preparing an article, an article obtained by said method, as well as the use of the α-functionalized ketone or the photopolymerizable composition as photoinitiator.

(METHYLSULFONYL)PHENYL-2-(5H)-FURANONES WITH OXYGEN LINK AS COX-2 INHIBITORS

The invention encompasses the novel compound of Formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising co