24691-21-2Relevant academic research and scientific papers
Total Synthesis of the Potent and Broad-Spectrum Antibiotics Amycolamicin and Kibdelomycin
Chen, Chenglong,Chen, Jie,Li, Chao,Yang, Shaoqiang
supporting information, p. 21258 - 21263 (2021/12/17)
The complex and intriguing structures of the antibiotics amycolamicin and kibdelomycin are herein confirmed through total synthesis. Careful titration of the synthetic products reveals that kibdelomycin is the salt form of amycolamicin. This synthesis emp
Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy
Sherer, Brian A.,Hull, Kenneth,Green, Oluyinka,Basarab, Gregory,Hauck, Sheila,Hill, Pamela,Loch III, James T.,Mullen, George,Bist, Shanta,Bryant, Joanna,Boriack-Sjodin, Ann,Read, Jon,Degrace, Nancy,Uria-Nickelsen, Maria,Illingworth, Ruth N.,Eakin, Ann E.
scheme or table, p. 7416 - 7420 (2012/02/04)
The pyrrolamides are a new class of antibacterial agents targeting DNA gyrase, an essential enzyme across bacterial species and inhibition results in the disruption of DNA synthesis and subsequently, cell death. The optimization of biochemical activity an
ANTIBACTERIAL PIPERIDINE DERIVATIVES
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Page/Page column 76-77, (2008/06/13)
Compounds of formula (I) and their pharmaceutically acceptable salts are described: Formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
CHEMICAL COMPOUNDS
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Page/Page column 59, (2008/06/13)
Compounds of formula (I) and their pharmaceutica11y acceptable salts are described:Processes for their preparation,pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described
TRICYCLIC DERIVATIVES OF AZETIDINE AND PYRROLE WITH ANTIBACTERIAL ACTIVITY
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Page/Page column 54, (2008/06/13)
Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
CHEMICAL COMPOUNDS
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Page/Page column 67, (2010/11/23)
Compounds of formula (I) and their pharmaceutically acceptable salts are described: Formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
