24706-47-6

Basic information

• Product Name: 3-((4-CHLOROPHENYL)AMINO)-5,5-DIMETHYLCYCLOHEX-2-EN-1-ONE
• Synonyms: 3-((4-CHLOROPHENYL)AMINO)-5,5-DIMETHYLCYCLOHEX-2-EN-1-ONE;AKOS UB-20225;2-cyclohexen-1-one, 3-[(4-chlorophenyl)amino]-5,5-dimethyl;3-[(4-chlorophenyl)amino]-5,5-dimethyl-1-cyclohex-2-enone;EU-0076734;ST5446868;ZINC00186189
• CAS NO: 24706-47-6
• Molecular Formula: C₁₄H₁₆ClNO
• Molecular Weight: 249.74
• Mol File: 24706-47-6.mol
• Article Data: 26

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-((4-CHLOROPHENYL)AMINO)-5,5-DIMETHYLCYCLOHEX-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((4-CHLOROPHENYL)AMINO)-5,5-DIMETHYLCYCLOHEX-2-EN-1-ONE(24706-47-6)
• EPA Substance Registry System: 3-((4-CHLOROPHENYL)AMINO)-5,5-DIMETHYLCYCLOHEX-2-EN-1-ONE(24706-47-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 24706-47-6(Hazardous Substances Data)

Upstream product

• 1001588-86-8 7,7-dimethyl-4-phenyl-4,6,7,8-tetrahydro-2H-1,3-benzoxazine-2,5(3H)-dione 
• 106-47-8 4-chloro-aniline 
• 126-81-8 dimedone 
• 3471-13-4 dimedone 

Downstream Products

• 1206477-95-3 C₂₈H₂₄Cl₃N₅O 
• 1255086-41-9 10-(4-chlorophenyl)-9-(2-thienyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dione 
• 1255086-51-1 2-amino-4-(3-bromophenyl)-1-(4-chlorophenyl)-7,7-dimethyl-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 1255086-59-9 2-amino-1-(4-chlorophenyl)-7,7-dimethyl-4-phenyl-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 1255086-54-4 2-amino-4-(2-chlorophenyl)-1-(4-chlorophenyl)-7,7-dimethyl-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 1255086-55-5 C₂₃H₂₂Cl₂N₂O 
• 1255086-53-3 2-amino-4-(4-bromophenyl)-1-(4-chlorophenyl)-7,7-dimethyl-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 1255086-57-7 2-amino-1-(4-chlorophenyl)-7,7-dimethyl-4-(4-methoxyphenyl)-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 1255086-58-8 2-amino-1-(4-chlorophenyl)-7,7-dimethyl-4-(4-methylphenyl)-1,4,5,6,7,8-hexahydroquinolin-5-one 
• 141076-61-1 10-(4-chlorophenyl)-9-(4-methylphenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dione 
• 1219128-74-1 10-(4-chlorophenyl)-9-(2,4-dichlorophenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dione 
• 1134961-10-6 3,3,6,6-tetramethyl-9-(4-bromophenyl)-10-(4-chlorophenyl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione 
• 1255086-38-4 10-(4-chlorophenyl)-9-(2-fluorophenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dione 
• 1255086-56-6 2-amino-1-(4-chlorophenyl)-4-(2,4-dichlorophenyl)-7,7-dimethyl-1,4,5,6,7,8-hexahydroquinolin-5-one 

Relevant articles and documents

A simple method for the rapid synthesis of 2-amino-7,7-dimethyl-5-oxo-1,4-diaryl-hexahydroquinoline-3-carboxamide derivatives

Abstract: Simple synthesis of oxoquinoline carboxamide derivatives via one-pot, multi-component reaction of enaminones derived from the addition of dimedone to various anilines with aromatic aldehydes and cyanoacetamide is described. Optimal reaction cond

A novel and reusable magnetic nanocatalyst developed based on graphene oxide incorporated strontium nanoparticles for the facial synthesis of β-enamino ketones under solvent-free conditions

A novel magnetic SrFeGO nanocatalyst (NC) was synthesized through a simple sol–gel technique by introducing strontium and iron oxide nanoparticles onto graphene. The synthesized NC was characterized using FT-IR and FE-SEM. Subsequently, the catalytic activity of SrFeGO was tested in a reaction between β-dicarbonyl compounds and aniline derivatives to gain β-enamino ketone derivatives under solvent-free conditions. It was found that SrFeGO NC is a potential catalyst for the synthesis of β-enamino ketones. The β-enamino ketone produced by such reactions could be isolated in high purity without the need for chromatographic purifications. The newly prepared magnetic graphene oxide nanocomposite could be recovered and reused for numerous times with no significant decrease in efficiency. Moreover, the protocol has the advantages of excellent yielding (up to 98%) in short a reaction time, benefitting an easy workup procedure and being environmentally friendly.

β-Enaminones over recyclable nano-CoFe2O4: a highly efficient solvent-free green protocol

Abstract: β-Enaminone and its derivatives have emerged among the finest bioactive intermediates. High yields of several β-enaminones (86–97%) are achieved through treatment of substituted aromatic and aliphatic amines with cyclic/acyclic 1,3-diketones, over the magnetically separable cobalt ferrite nanoparticles (CoFe2O4 NPs). The latter was prepared upon co-precipitation. Its purity, fine crystallinity, elemental distributions, morphology, magnetic features, and thermal stability were confirmed by Fourier transform infrared, X-ray diffraction, energy dispersive X-ray spectrometry, scanning electron microscopy, vibrating sample magnetometry, and thermal gravimetric analysis analyses. Thus, CoFe2O4 NPs acted as an excellent green heterogeneous nanocatalyst for synthesis of β-enaminones and gave good recyclability, while showing insignificant loss of their activity. Graphical Abstract: [Figure not available: see fulltext.].