247079-77-2Relevant articles and documents
Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands
De Amici, Marco,Conti, Paola,Fasoli, Ezio,Barocelli, Elisabetta,Ballabeni, Vigilio,Bertoni, Simona,Impicciatore, Mariannina,Roth, Bryan L.,Ernsberger, Paul,De Micheli, Carlo
, p. 739 - 748 (2007/10/03)
A set of novel heterocyclic ligands (7a-9a, 7b-9b, and 9c) structurally related to oxotremorine 2 was designed, synthesized, and tested at muscarinic receptor subtypes. In the binding experiments at cloned hm1-5, the presence of the 2-methylimidazole/2-me