247107-71-7Relevant academic research and scientific papers
Total synthesis of the novel immunosuppressant sanglifehrin A
Nicolaou,Murphy,Barluenga,Ohshima,Wei,Xu,Gray,Baudoin
, p. 3830 - 3838 (2007/10/03)
The total synthesis of the novel immunosuppressant sanglifehrin A (SFA, 1) is described. The approach is flexible, convergent, and stereoselective. The use of Paterson's aldol methodology was pivotal for the preparation of the novel, highly substituted sp
Total synthesis of sanglifehrin A
Nicolaou,Xu, Jinyou,Murphy, Fiona,Barluenga, Sofia,Baudoin, Olivier,Wei, Heng-Xu,Gray, David L. F.,Ohshima, Takashi
, p. 2447 - 2451 (2007/10/03)
The immunosuppressive agent sanglifehrin A has been prepared for the first time by total synthesis. The construction of the macrocyclic unit of the target molecule was achieved through a selective intramolecular Stille coupling, and the spirolactam unit b
