247132-53-2

Upstream product

• 247132-52-1 benzyl 7-(2-iodoethoxy)-1,2,3,4-tetrahydroisoquinolin-2-carboxylate 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 39989-39-4 7-methoxyisoquinoline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 247132-40-7 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid benzyl ester 
• 110192-19-3 7-hydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 43207-78-9 7-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1126-09-6 4-carbethoxypiperidine 

Downstream Products

• 247132-54-3 benzyl 7-[2-[4-ethoxycarbonyl-1-(pyridin-4-yl)piperidin-4-yl]ethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring

A series of novel 2,7-disubstituted tetrahydroisoquinoline derivatives were designed and synthesized. Among these derivatives, compounds 1 and 2 exhibited potent inhibitory activity against factor Xa (FXa) and good selectivity with respect to other serine

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen