247233-85-8Relevant academic research and scientific papers
Inhibitors of the C2-symmetric HIV-1 protease: Nonsymmetric binding of a symmetric cyclic sulfamide with ketoxime groups in the P2/P2' side chains
Hultén, Johan,Andersson, Hans O.,Schaal, Wesley,Danielson, Helena U.,Classon, Bj?rn,Kvarnstr?m, Ingemar,Karlén, Anders,Unge, Torsten,Samuelsson, Bertil,Hallberg, Anders
, p. 4054 - 4061 (1999)
Symmetric cyclic sulfamides, substituted in the P2/P2' position with functional groups foreseen to bind preferentially to the S2/S2' subsites of HIV-1 protease, have been prepared. Despise efforts to promote a symmetric binding, the sulfamides seemed pron
