24756-13-6Relevant academic research and scientific papers
Pyridine-Catalysed Desulfonylative Addition of β-Diketones to Arylazosulfones via Diaziridine Rearrangement
Ji, Xin,Meng, Ling-Guo,Xu, Hailong,Wang, Lei
supporting information, p. 1142 - 1146 (2020/12/31)
A pyridine-catalysed desulfonylative addition of β-diketones to arylazosulfones was developed to obtain diazenyl β-dicarbonyl compounds. The aryldiazenyl group was observed in the desired product from arylazosulfones, and this diazenylation reaction was achieved via a possible rearrangement process based on diaziridine ring cleavage. The scope of the protocol was investigated and a plausible mechanism was given. (Figure presented.).
Aryldiazenyl Radicals from Arylazo Sulfones: Visible Light-Driven Diazenylation of Enol Silyl Ethers
Othman Abdulla, Havall,Scaringi, Simone,Amin, Ahmed A.,Mella, Mariella,Protti, Stefano,Fagnoni, Maurizio
supporting information, p. 2150 - 2154 (2020/03/04)
A versatile protocol for the diazenylation of enol silyl ethers under visible light irradiation is presented herein. The reaction is based on the underused reaction of a nitrogen-based radical (the diazenyl radical) with an enol silyl ether. Arylazo sulfones were used as photoactivatable precursors of these diazenyl radicals. The resulting azaderivatives are potentially bioactive compounds as well as starting materials for the synthesis of N-containing heterocycles. (Figure presented.).
Arylazo-3,5-dimethylisoxazoles: Azoheteroarene Photoswitches Exhibiting High Z-Isomer Stability, Solid-State Photochromism, and Reversible Light-Induced Phase Transition
Devi, Sudha,Kumar, Pravesh,Sah, Chitranjan,Srivastava, Anjali,Venkataramani, Sugumar
supporting information, (2019/08/21)
Reversibly photoswitchable phenylazo-3,5-dimethylisoxazole and 37 aryl-substituted derivatives were synthesized. Excellent photoswitching ability of these compounds in solution and the solid state was demonstrated. Through kinetics studies by means of NMR spectroscopy, high Z-isomer stability was demonstrated. Interestingly, the majority of the derivatives showed light-induced contrasting color changes in solution and the solid state. Besides, many of the derivatives exhibit partial phase transition upon UV irradiation. The highlight of this class of photoswitches is the reversible light-induced phase transition between solid and liquid phases in the parent compound, which can be used in patterned crystallization. These results show that this new class of azoheteroarene based photoswitches has opportunities to be useful in various domains.
Synthesis, characterization and antibacterial screening of new pyrazole and pyrazoline-5-one derivatives
Nagaraju,Srinivasulu,Doraswamy,Venkata Ramana
experimental part, p. 293 - 298 (2012/03/11)
A series of N′-(p-toluene sulphonyl)-3-methyl-4-(substituted arylhydrazono)-2-pyrazoline-5-ones and N′-(2-hydroxybenzoyl)-3,5-dimethyl- 4-(substituted arylazo)pyrazoles have been synthesized and characterized by chemical analysis, IR and 1H NMR spectral data. The compounds have been screened for antibacterial activity against Staphylococcus aureus and Escherichia coli.
Spectral and cyclic voltammetric studies on some intramolecularly hydrogen bonded arylhydrazones: Crystal and molecular structure of 2-(2-(3-nitrophenyl)hydrazono)-5,5-dimethylcyclohexane-1,3-dione
Sethukumar,Arul Prakasam
experimental part, p. 250 - 257 (2010/03/30)
A series of arylhydrazone derivatives (1-7) were prepared by the coupling of acetylacetone/dimedone with respective aromatic diazonium salts and characterized by IR, 1H and 13C NMR spectra. The IR and NMR spectral data clearly manife
Pyridazinone compounds
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Page/Page column 41, (2010/08/08)
The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0): wherein R1 represents a substituent, R2 represents a hydrogen atom, or a substituent, R3 represents a hydrogen atom, or a substituent, Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.
Reaction of (cyano)thioacetamide with arylhydrazones of β-diketones: Novel synthesis of 2(1H)-pyridinethiones, thieno[2,3-b]pyridines, and pyrazolo[3,4-b]pyridines
Elgemeie, Galal Eldin Hamza,El-Zanate, Ali Mahmoud,Mansour, Abdel-Kader E.
, p. 555 - 561 (2017/03/31)
A novel synthesis of 2(1H)-pyridinethiones, thieno[2,3-b]pyridines and pyrazolo[3,4-b]pyridines utilizing (cy-ano)thioacetamide and arylhydrazones of 1,3-diketones as starting components is described.
Laser Flash Photolysis of Aromatic Azo-hydrazone Systems
McVie, James,Mitchell, Alastair D.,Sinclair, Roy, S.,Truscott, T. George
, p. 286 - 290 (2007/10/02)
Laser flash photolysis using 347 nm excitation and pulse radiolysis have been used to study the transient species produced from solutions of a series of eight hydrazone compounds synthesised from substituted (R1, R2) 1,3-diones coupled to substituted (Ar) aromatic amines.Three classes of transient behaviour were found in hexane solution.Compound (8) gave a very short-lived transient (t1/2 ca. 45 ns, λmax. 510 nm) which was identified as a triplet species.The other three compounds from unsymmetrical dione derivatives gave short-lived transients (t1/2 ca. 50-100 μs) in the spectral region 440-460 nm and long-lived transients (t1/2 ca. 0.5-2.0 s) occuring at ca. 425 nm, whereas the four symmetrical derivatives (R1=R2) gave only the short-lived transients in the region 450-470 nm.The lifetimes of the longer-lived transients were shown to be dependent on solvent polarity and added acid.It is proposed that the longer-lived transients are associated with isomerism about the C=N bond, induced by photoexcitation into the singlet excited state.Rate constants for quenching of various triplet species by three of the hydrazones were determined and shown to correlate with the triplet energy of the compounds being quenched.Assuming quenching occurred by electronic energy transfer the triplet energies of the hydrazones were estimated to lie in the range 150-190 kJ mol-1.The photochemical breakdown products arising from extensive u. v. irradiation have been examined by chromatographic and spectroscopic techniques.It was shown that the compounds are relatively stable to irradiation above 330 nm.
