247592-09-2Relevant articles and documents
Use of tetrabenzo[a,c,g,i]fluorene as an anchor group for the solid/solution phase synthesis of the quinolone antibacterial, ciprofioxacin
Hay, Alastair M.,Hobbs-Dewitt, Sheila,MacDonald, Alasdair A.,Ramage, Robert
, p. 1979 - 1985 (1999)
The affinity of tetrabenzo[a,c,g,i]fluorene (Tbf) for charcoal has been applied successfully to provide an alternative to existing solid phase synthesis methodology. In a synthesis of the quinolone antibacterial, Ciprofloxacin, traditional solution phase synthesis has been coupled with efficient pseudo-solid phase purification.
