24765-57-9

Basic information

• Product Name: 2,2-DI-N-BUTYL-1,3-PROPANEDIOL
• Synonyms: 2-N-BUTYL-2-(HYDROXYMETHYL)-1-HEXANOL;2,2-DI-N-BUTYL-1,3-PROPANEDIOL;2,2-DIBUTYL-1,3-PROPANEDIOL;2,2-DIBUTYLPROPANE-1,3-DIOL;2-(But-1-yl)-2-(hydroxymethyl)hexan-1-ol, 5,5-Bis(hydroxymethyl)nonane;2,2-Di(but-1-yl)propane-1,3-diol;2,2-Dibutyl-1,3-propanediol 97%
• CAS NO: 24765-57-9
• Molecular Formula: C₁₁H₂₄O₂
• Molecular Weight: 188.31
• Product Categories: Organic Building Blocks;Oxygen Compounds;Polyols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 24765-57-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 41-43 °C(lit.)
• Boiling Point: 125-130°C 1mm
• Flash Point: >230 °F
• Appearance: /
• Density: 0.9314 (rough estimate)
• Vapor Pressure: 0.000991mmHg at 25°C
• Refractive Index: 1.4595 (estimate)
• PKA: 14.55±0.10(Predicted)
• Water Solubility: Soluble in water.
• BRN: 1699746
• CAS DataBase Reference: 2,2-DI-N-BUTYL-1,3-PROPANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DI-N-BUTYL-1,3-PROPANEDIOL(24765-57-9)
• EPA Substance Registry System: 2,2-DI-N-BUTYL-1,3-PROPANEDIOL(24765-57-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 24765-57-9(Hazardous Substances Data)

Usage

Uses

2,2-Di-n-butyl-1,3-propanediol is used as pharmaceutical intermediates.

InChI:InChI=1/C11H24O2/c1-3-5-7-11(9-12,10-13)8-6-4-2/h12-13H,3-10H2,1-2H3

Upstream product

• 101853-00-3 diethyl-malonic acid dibutyl ester 
• 124-38-9 carbon dioxide 
• 596-75-8 diethyl dibutylmalonate 

Downstream Products

• 102887-77-4 2-Hydroxymethyl-2-butyl-hexanol-bis-<4-brom-benzolsulfonat> 
• 109820-93-1 2-Hydroxymethyl-2-butyl-hexanol-mono-<4-brom-benzolsulfonat> 
• 1373485-62-1 8-(4-(diphenylamino)styryl)-3,3-dibutyl-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine-6-carbaldehyde 
• 1373485-53-0 3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine 
• 100453-54-1 5,5-dibutyl-dihydro-[1,3]oxazine-2,4-dione 

Relevant articles and documents

Electron transfer reduction of unactivated esters using SmI 2-H2O

The reduction of unactivated esters using samarium diiodide is reported for the first time. The optimised protocol allows for the reduction of primary, secondary and tertiary alkyl esters in excellent yields and is competitive with reductions mediated by metal hydrides and alkali metals.

Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides

A process for preparing enantiomerically enriched tetrahydrobenzothipeine oxides comprises cyclizing an enantiomerically enriched aryl-3-propanalsulfoxide wherein the sulfur atom of the aryl-3-propanalsulfoxide is a chiral center.

Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake

Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.