24772-63-2

Usage

Uses

1. Used in Polymer Solar Cells:
1,8-Diiodoocatane is used as an additive to enhance the power conversion efficiency of polymer solar cells. Its incorporation into the solar cell structure helps improve the overall performance and efficiency of the device.
2. Used in Bulk Heterojunction Solar Cells:
In the context of bulk heterojunction solar cells, 1,8-diiodooctane is employed as a processing additive. It aids in optimizing the morphology of the active layer, which in turn leads to improved efficiency of the solar cells based on regioregular poly(3-hexylthiophene).
3. Used in Chemical Synthesis:
1,8-Diiodoocatane can also be utilized as a reagent or intermediate in various chemical synthesis processes, particularly in the pharmaceutical and materials science industries, due to its unique chemical properties and reactivity.

InChI:InChI=1/C8H16I2/c9-7-5-3-1-2-4-6-8-10/h1-8H2

Upstream product

• 629-41-4 1,8-Octanediol 
• 61575-01-7 1,8-diphenoxyoctane 
• 10034-85-2 hydrogen iodide 
• 4549-32-0 1,8-dibromooctane 

Downstream Products

• 693-23-2 1,12-dodecanedioic acid 
• 66919-99-1 1,8-bis(phenylthio)octane 
• 102599-99-5 N₁,N₈-diphenyloctane-1,8-diamine 
• 51306-09-3 1,8-dimethoxyoctane 
• 138942-66-2 C₉₄H₇₄N₁₀⁽²⁺⁾*2I^(1-) 
• 118311-21-0 Bis-(N-methyl-N-cyclohexylamino)octane dimethiodide 
• 118311-22-1 Bis-(N-methyl-N-phenylamino)octane dimethiodide 
• 179537-91-8 10-iodo-2-[(R,S)-cyclopentyl]decanoic acid benzyl ester 
• 111-65-9 octane 
• 371760-07-5 (26-benzoyl-2,9,15,24-tetraoxa-tricyclo[23.3.1.1^10,14]triaconta-1⁽²⁸⁾,10⁽³⁰⁾,11,13,25⁽²⁹⁾,26-hexaen-13-yl)-phenyl-methanone 
• 371760-04-2 C₄₂H₄₀O₆ 
• 830-13-7 cyclododecanone 
• 1037167-42-2 C₁₆H₂₁IO₃ 

Relevant academic research and scientific papers

Highly Selective Radical Monoreduction of Dihalides Confined to a Dynamic Supramolecular Host

Reduction of alkyl dihalide guests (2–5 and 7) with trialkylsilanes (R3SiH) was performed in water-soluble host 1 to investigate the effects of confinement on fast radical reactions (k≥103 m?1 s?1). High selectivity (>95 %) for mono-reduced products was observed for primary and secondary dihalide guests under mild conditions. The results highlight the importance of host–guest complexation rates to modulate the product selectivity in radical reactions.

Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

Herein, we report the development of bitopic ligands aimed at targeting the orthosteric binding site (OBS) and a metastable binding site (MBS) within the same receptor unit. Previous molecular dynamics studies on ligand binding to the β2-adrenergic receptor (β2AR) suggested that ligands pause at transient, less-conserved MBSs. We envisioned that MBSs can be regarded as allosteric binding sites and targeted by homobivalent bitopic ligands linking two identical pharmacophores. Such ligands were designed based on docking of the antagonist (S)-alprenolol into the OBS and an MBS and synthesized. Pharmacological characterization revealed ligands with similar potency and affinity, slightly increased β2/β1AR-selectivity, and/or substantially slower β2AR off-rates compared to (S)-alprenolol. Truncated bitopic ligands suggested the major contribution of the metastable pharmacophore to be a hydrophobic interaction with the β2AR, while the linkers alone decreased the potency of the orthosteric fragment. Altogether, the study underlines the potential of targeting MBSs for improving the pharmacological profiles of ligands.

Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site

Falcarinol and stipudiol are natural products with potent anti-cancer activity found in several vegetables. Here, we use a chemical proteomic strategy to identify ALDH2 as a molecular target of falcarinol in cancer cells and confirm enzyme inhibition via covalent alkylation of the active site. Furthermore, the synthesis of stipudiol led to the observation that ALDH2 exhibits preference for alkynol-based binders. Inhibition of ALDH2 impairs detoxification of reactive aldehydes and limits oxidative stress response, two crucial pathways for cellular viability.

Ionic liquids as reagents and solvents in conjunction with microwave heating: Rapid synthesis of alkyl halides from alcohols and nitriles from aryl halides

We show that using ionic liquids as reagents in conjunction with microwave heating it is possible to prepare primary alkyl halides from the corresponding alcohols rapidly. Using ionic liquids as solvents in conjunction with microwave heating it is possible to prepare aryl nitriles from the corresponding aryl bromides or iodides. The scope and limitations of using microwave-promotion as a tool in these reactions is discussed.

Low-Frequency Raman Spectra of Even α,ο-Disubstituted n-Alkanes

Low-frequency Raman spectra of even α,ο-disubstituted n-alkanes have been recorded.The major features in the spectra arise from whole-chain longitudinal and bending vibrations.The effects of end group, chain lenght, and temperature on the frequencies of these vibrations are described, and the frequencies of the longitudinal vibrations are interpreted in terms of the chain model of Minoni and Zerbi.