24772-65-4Relevant articles and documents
Radical Reactions in Cavitands Unveil the Effects of Affinity on Dynamic Supramolecular Systems
Angamuthu, Venkatachalam,Petroselli, Manuel,Rahman, Faiz-Ur,Rebek, Julius,Yu, Yang,Zhao, Xinluo
supporting information, (2020/02/18)
Radical reduction of alkyl halides and aerobic oxidation of alkyl aromatics are reported using water-soluble container compounds (1 and 2). The reductions involve α,ω-dihalides (4-8 and 10) with radical initiators in cavitand hosts with varied binding affinities. Product distributions lead to general guidelines for the use of dynamic supramolecular systems with fast reactions. The binding of guest substrates in the hosts must show high affinities (Ka> 103M-1) to ensure that the reactions take place under confinement in the containers.
Synthesis of both enantiomers of akolactone B and (+)-ancepsenolide
Hikosaka, Gen,Hattori, Yasunao,Makabe, Hidefumi
, p. 1367 - 1371 (2014/12/11)
The syntheses of (+)- and (-)-akolactone B and (+)-ancepsenolide were accomplished using a Pd-catalyzed carbonylation. As to the absolute configuration of akolactone B, making a comparison of the specific rotation of both enantiomers of synthetic akolactone B and the natural compound suggests that the absolute configuration at the 4-position of akolactone B is (R).
Quaternary bis-ammonium salt precursors and their uses as prodrugs having an antiparasitic activity
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Page/Page column 17, (2010/02/14)
The invention concerns drug precursors with antimalarial effect, characterised in that it consists in quaternary bis-ammonium salts of general formula (I) wherein A and A′, identical or different, are respectively either a group A1 and A′1 of formula (1)
