2479-90-5 Usage
Uses
Used in Pharmaceutical Industry:
1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3(O->1BETA)-D-GLYCOPYRANOSIDURONIC ACID is used as a pharmaceutical compound for its role in the endocrine system. It is derived from 17β-Estradiol, which is the major estrogen hormone secreted by the premenopausal ovary, making it a crucial component in the development and maintenance of various physiological processes.
Used in Research and Development:
In the field of research and development, 1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3(O->1BETA)-D-GLYCOPYRANOSIDURONIC ACID serves as an essential compound for studying the effects and mechanisms of estrogen hormones. This knowledge can be applied to develop new drugs and therapies targeting estrogen-related conditions and disorders.
Used in Diagnostics:
1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3(O->1BETA)-D-GLYCOPYRANOSIDURONIC ACID can be utilized in diagnostic tests to measure the levels of Estrone β-D-Glucuronide in biological samples. This information can be valuable for assessing the hormonal balance and diagnosing conditions related to estrogen levels, such as menopause, pregnancy, and certain types of cancer.
Used in Hormone Replacement Therapy:
As a metabolite of 17β-Estradiol, 1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3(O->1BETA)-D-GLYCOPYRANOSIDURONIC ACID may be used in hormone replacement therapy to alleviate symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness. It can also help maintain bone density and reduce the risk of osteoporosis.
Used in Fertility Treatments:
In the field of fertility treatments, 1,3,5(10)-ESTRATRIEN-3-OL-17-ONE 3(O->1BETA)-D-GLYCOPYRANOSIDURONIC ACID may be employed to study and understand the role of estrogen hormones in reproductive health. This knowledge can be applied to develop new treatments and therapies for infertility and other reproductive disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 2479-90-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,7 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2479-90:
(6*2)+(5*4)+(4*7)+(3*9)+(2*9)+(1*0)=105
105 % 10 = 5
So 2479-90-5 is a valid CAS Registry Number.
InChI:InChI=1/C24H30O8/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30)/t14-,15-,16+,18+,19+,20-,21+,23-,24+/m1/s1
2479-90-5Relevant academic research and scientific papers
The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: Improved practicality and broader scope
Ma, Paul,Kanizaj, Nicholas,Chan, Shu-Ann,Ollis, David L.,McLeod, Malcolm D.
supporting information, p. 6208 - 6214 (2014/08/05)
A library of steroid glucuronides was prepared using the glucuronylsynthase derived from Escherichia coli β-glucuronidase, followed by purification using solid-phase extraction. A representative range of steroid substrates were screened for synthesis on t
Synthesis of β-glucuronides of estradiol, ethynylestradiol and estrone
Werschkun, Barbara,Gorziza, Karin,Thiem, Joachim
, p. 629 - 637 (2007/10/03)
Improved syntheses for the 3-β-D-glucuronides of the steroidal sex hormones 17β-estradiol, 17α-ethynylestradiol and estrone are reported employing boron trifluoride diethyl etherate catalysis with tetraacetylated glucuronic acid or the corresponding imidate.
