247918-68-9Relevant academic research and scientific papers
1-[(1-Substituted-4-piperidinyl)methyl]-4-piperidine derivative, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
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, (2008/06/13)
Compound of the formula (I): STR1wherein Ar is a group of the following formula (Ar-1) or (Ar-2): STR2A is a group of the formula:--Z--N(Q 1)(Q 2), --CO--R 7or--(CH 2)p--CH(R 8)--COR 9,or a pharmaceutically acceptable acid addition salt thereof, a process for preparing the same, a pharmaceutical composition containing the same, and intermediates therefor. The compounds of the present invention show a potent affinity for 5-HT 4 receptors, and they are useful as a gastrointestinal motility enhancer or a gastrointestinal prokinetic agent.
