248274-16-0

Usage

Uses

Used in Pharmaceutical Industry:
1-(5-(trifluoromethyl)pyridin-2-yl)ethanone is used as a building block for the synthesis of various biologically active compounds due to its unique chemical and pharmacological properties.
Used in Drug Development:
1-(5-(trifluoromethyl)pyridin-2-yl)ethanone is used as a versatile intermediate in the synthesis of anti-inflammatory, antimicrobial, and antifungal agents, contributing to the development of new medications.
Used in Agrochemical Preparation:
1-(5-(trifluoromethyl)pyridin-2-yl)ethanone is used as a reagent in the preparation of agrochemicals, aiding in the development of effective products for agricultural applications.
Used in Material and Catalyst Development:
1-(5-(trifluoromethyl)pyridin-2-yl)ethanone is utilized in the development of new materials and catalysts, showcasing its potential applications beyond the pharmaceutical industry.

Upstream product

• 95727-86-9 2-cyano-5-trifluoro-methylpyridine 
• 75-16-1 methylmagnesium bromide 
• 50488-42-1 2-bromo-5-(trifluoromethyl)pyridine 
• 80194-69-0 5-(trifluoromethyl)picolinic acid 

Downstream Products

• 849370-44-1 t-butyl 4-[1-hydroxy-1-(5-trifluoromethylpyridin-2-yl)ethyl]-2-methylcarbanilate 

Relevant academic research and scientific papers

ANTIMICROBIAL AGENTS

The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.

SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT

The present invention is to provide a novel agrigultural chemical, particularly an insecticide or acaricide, and discloses a substituted benzanilide compound represented by the formula (1): wherein W1 and W2 each independently repres

Preparation of 2-substituted pyridines

This invention relates to a process for preparing 2-substituted pyridines via metal halogen exchange with sec-butyllithium on optionally substituted 2-bromo or 2-iodopyridines. The resulting lithopyridine intermediate is reacted with an electrophile to provide the desired 2-substituted pyridine. The substitution of sec-butyllithium for n-butyllithium in such a process results in an enhanced yield and purity of the desired 2-substituted pyridine.

Preparation of 2-substituted pyridines

This invention relates to a process for preparing 2-substituted pyridines via metal halogen exchange with sec-butyllithium on optionally substituted 2-bromo or 2-iodopyridines. The resulting lithopyridine intermediate is reacted with an electrophile to provide the desired 2-substituted pyridine. The substitution of sec-butyllithium for n-butyllithium in such a process results in an enhanced yield and purity of the desired 2-substituted pyridine.