248274-16-0 Usage
General Description
1-(5-(trifluoromethyl)pyridin-2-yl)ethanone, also known as trifluoromethylpyridinyl ketone, is a chemical compound with the molecular formula C9H7F3NO. It is a yellow crystalline solid that is commonly used in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds. 1-(5-(trifluoromethyl)pyridin-2-yl)ethanone contains a pyridine ring with a trifluoromethyl group and an ethanone group, giving it unique chemical and pharmacological properties. The trifluoromethylpyridinyl ketone is known for its role as a versatile intermediate in drug development, particularly in the synthesis of anti-inflammatory, antimicrobial, and antifungal agents. Additionally, it is also used as a reagent in the preparation of agrochemicals and in the development of new materials and catalysts. Due to its potential applications in medicine and other industries, the trifluoromethylpyridinyl ketone is an important compound with diverse uses.
Check Digit Verification of cas no
The CAS Registry Mumber 248274-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,8,2,7 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 248274-16:
(8*2)+(7*4)+(6*8)+(5*2)+(4*7)+(3*4)+(2*1)+(1*6)=150
150 % 10 = 0
So 248274-16-0 is a valid CAS Registry Number.
248274-16-0Relevant articles and documents
ANTIMICROBIAL AGENTS
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, (2015/05/26)
The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.
Preparation of 2-substituted pyridines
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, (2008/06/13)
This invention relates to a process for preparing 2-substituted pyridines via metal halogen exchange with sec-butyllithium on optionally substituted 2-bromo or 2-iodopyridines. The resulting lithopyridine intermediate is reacted with an electrophile to provide the desired 2-substituted pyridine. The substitution of sec-butyllithium for n-butyllithium in such a process results in an enhanced yield and purity of the desired 2-substituted pyridine.