248279-36-9

Upstream product

• 20989-19-9 (2S)-2-amino-3-(4-methoxyphenyl)propan-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 915027-00-8 [1-(tert-butyl-dimethyl-silanyloxymethyl)-2-(4-methoxy-phenyl)-ethyl]-(1,4-dithia-spiro[4.5]dec-8-ylidene)-amine 
• 1258684-44-4 C₃₅H₅₄N₂O₄Si 
• 1258684-45-5 C₃₅H₅₄N₂O₄Si 
• 1258684-43-3 C₂₇H₄₄INO₄Si 
• 915027-01-9 (1S)-[2-(tert-butyldimethylsiloxy)-1-(4-methoxybenzyl)ethyl]-N-[8-(1-methoxypropa-1,2-dienyl)-1,4-dithiaspiro[4.5]dec-8-yl]amine 
• 915027-02-0 (1'S)-9-[2-(tert-butyldimethylsiloxy)-1-(4-methoxybenzyl)ethyl]-12-methoxy-1,4-dithia-9-azadispiro[4.2.4.2]tetradec-11-ene 
• 915027-08-6 (S)-1-[2-(tert-butyldimethylsiloxy)-1-(4-methoxybenzyl)ethyl]-4-methoxy-1-azaspiro[4.5]dec-3-ene-8-one 
• 915027-11-1 (5S,6R,7R,11S)-6-hydroxy-1-methoxy-5-(4-methoxybenzyl)-6,7,9,10-tetrahydro-3H-7,10a-methanopyrrolo[1,2-a]azocine-8(5H)-one 
• 915027-09-7 (S)-1-[2-hydroxy-1-(4-methoxybenzyl)ethyl]-4-methoxy-1-azaspiro[4.5]dec-3-ene-8-one 
• 915027-03-1 (S)-2-(4-methoxy-8-oxo-1-azaspiro[4.5]dec-3-en-1-yl)-3-(4-methoxyphenyl)propanal 

Relevant academic research and scientific papers

Efficient approach to the azaspirane core of FR 901483

(Chemical Equation Presented) An efficient approach to the azaspirane core of FR 901483 is described employing lithiated methoxyallene as a crucial C3 building block and a suitably protected enantiopure ketimine as the second component. The resulting dihy

Synthesis of enantiopure 1-azaspiro[4.5]decanes by iodoaminocyclization of allylaminocyclohexanes

The 5-endo iodine-promoted ring closure of 4-allyl-4-(alkylamino) cyclohexanone derivatives gives the corresponding 1-azaspiro[4.5]decanes in good yields. The reaction was tested with enantiopure homoallylamines to evaluate the diastereoselectivity of the process and to provide a route for possible intermediates to the natural products embodying this azabicyclic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.