24890-62-8

Upstream product

• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 108-88-3 toluene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 611-15-4 1-methyl-2-vinyl-benzene 
• 95-46-5 2-methylphenyl bromide 
• 32117-52-5 1-(1-(4-methoxyphenyl)ethylidene)-2-tosylhydrazine 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 932-31-0 ortho-tolylmagnesium bromide 
• 122948-71-4 1-<α-(p-tolylsulfonyl)ethyl>-4-methoxybenzene 
• 1093686-51-1 O,O-diethyl 1-o-tolylvinylphosphate 
• 93296-09-4 4-methoxyphenylzinc chloride 

Downstream Products

• 41204-59-5 (4-methoxyphenyl)(2-methylphenyl)methanone 

Relevant academic research and scientific papers

Synthesis and characterization of Pd(II) and Ru(II) complexes of tetradentate N,N,N,N-(Diphosphinomethyl)amine ligands: Catalytic properties in transfer hydrogenation and heck coupling reactions

– Tetradentate N,N,N,N-(diphosphinomethyl)amine ligands and their Pd(II) and Ru(II) complexes were synthesized under a nitrogen atmosphere using Schlenk technique. The synthesized ligands and the complexes were characterized with 1H- and 31P-NMR, FT-IR, TG/DTA, and elemental analysis techniques. Pd(II) Complexes were used as catalysts in Heck coupling reactions and Ru(II) complexes were tried in transfer hydrogenation reactions of acetophenone derivatives. According to the results, L4-Pd(II) complex showed the best catalytic activity in the Heck coupling reaction of p-methylbromobenzene with o-chlorostyrene. It was confirmed that the reduction of bromo and chloroacetophenones in all catalysts the conversions were higher. The results showed that Ru(II) complexes as efficient catalysts and up to 99percent conversions was occurred with bromo and chloro acetophenones in K2CO3/isopropyl alcohol media at 80 °C.

Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application

Synthesis, temperature-dependent NMR structure investigation and utilization of a new, stable and easily accessible aryl-diadamantylphosphine ligand family is reported. The bulky and electron-rich phosphorus center of the ligand enhances the catalytic activity of palladium in cross-coupling reactions of sterically demanding ortho-substituted aryl halides. In our study, we demonstrated the synthetic applicability of the new phosphine ligands in Buchwald-Hartwig and tosyl hydrazone coupling reactions.

Traceless directing group mediated branched selective alkenylation of unbiased arenes

Owing to the synthetic importance of branched olefinated products, we report palladium catalyzed formation of branched olefins facilitated by a C-H activation based protocol. This involves selective insertion of olefins and subsequent decarboxylation using a completely unbiased benzene ring as the starting precursor. The significance of the protocol has been further highlighted by exhibition of functionality tolerance along with a late-stage modification of the branched olefinated products leading to the formation of other functionalized molecules.

Nickel-catalyzed Kumada reaction of tosylalkanes with Grignard reagents to produce alkenes and modified arylketones

Open a new door: The first example of alkene synthesis from alkyl electrophiles with Grignard reagents using the Kumada cross-coupling reaction strategy is reported. This method opens a new door for the Kumada cross-coupling reaction, allowing alkenes to be prepared from the reaction of tosylalkanes with Grignard reagents. Copyright

Studies on the 1,2-migrations in Pd-catalyzed negishi couplings with JosiPhos ligands

(Chemical Equation Presented) We report an initial investigation with the goal of determining the factors that control the 1,2-migration in the Negishi cross-coupling, which is promoted by palladium catalyst systems generated with JosiPhos ligands. Severa