248920-15-2

Usage

Category

Organic compound, phenyl-containing alcohols

Physical State

Colorless or pale yellow liquid at room temperature

Odor

Subtle, sweet

Uses

Synthesis of pharmaceuticals and other fine chemicals, reagent in the preparation of biologically active molecules

Reactivity

Versatile building block in organic synthesis

Toxicity

Known to exhibit toxic and irritant properties, should be handled with caution.

Upstream product

• 248920-11-8 2-bromo-3-methylphenyl acetic acid 
• 248920-09-4 2-(2’-bromo-3’-methylphenyl)acetonitrile 
• 66790-58-7 2-bromo-1-(bromomethyl)-3-methylbenzene 
• 576-22-7 2-Bromo-m-xylene 
• 512786-36-6 (2-bromo-3-methyl-phenyl)-acetic acid methyl ester 

Downstream Products

• 512786-28-6 2-bromo-1-(2-chloro-ethyl)-3-methyl-benzene 

Relevant academic research and scientific papers

Substitution-Controlled Selective Formation of Hexahydrobenz[ e]isoindoles and 3-Benzazepines via In(OTf)3-Catalyzed Tandem Annulations

A dramatic N-substituent controlled tandem annulation of 2-(2-(2-bromoethyl)phenyl)-1-sulfonylaziridines with 1,3-dicarbonyl compounds has been developed. When the N-substituent was a 4-methylbenzenesulfonyl group (Ts), sequential ring opening of aziridin

A new synthesis of 3-substituted-1H-indenes through reaction of o-(β-magnesioalkyl)phenylmagnesium dihalides with carboxylate esters

A new synthesis of 3-substituted-1H-indenes has been developed through the reaction of o-(β-magnesioalkyl)phenylmagnesium dihalides with carboxylate esters, followed by dehydration of the intermediate 1-substituted-1-indanols. Di-Grignard reagents allowing the synthesis of 3-substituted-, 2-methyl-3-substituted-, and 4-methyl-3-substituted-1H-indenes have been prepared, with overall yields for the two-step sequence ranging from 45 to 95%.