2492-23-1

Usage

Uses

suzuki reaction

InChI:InChI=1/C25H19Cl2P/c26-21-17-16-20(25(27)18-21)19-28(22-10-4-1-5-11-22,23-12-6-2-7-13-23)24-14-8-3-9-15-24/h1-19H

Upstream product

• 94-99-5 2,4-Dichlorobenzyl chloride 
• 603-35-0 triphenylphosphine 

Downstream Products

• 15866-68-9 1-(2,4-Dichlorphenyl)-4-(p-nitrophenyl)butadien 
• 15866-65-6 1-(2,4-Dichlorphenyl)-4-(m-nitrophenyl)-1,3-butadien 
• 60824-75-1 8-(2,4-Dichlorbenzyliden)-7,9-diphenyl-8H-cyclopentacenaphthylen 
• 60824-71-7 6-(2,4-Dichlorpenyl)-1,2,3,4-tetraphenyl-fulven 
• 101910-00-3 (3aR,5S,6aR)-5-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 19671-08-0 2-<2,4-Dichlor-phenyl>-2-<4-methyl-phenyl>-1,1,1-trichlor-aethan 
• 101910-02-5 (3R,5R)-5-[2-(2,4-Dichloro-phenyl)-ethyl]-tetrahydro-furan-2,3-diol 
• 90691-50-2 (4R,6R)-6-[2-(2,4-Dichloro-phenyl)-ethyl]-tetrahydro-pyran-2,4-diol 
• 101910-01-4 (3aR,5R,6aR)-5-[2-(2,4-Dichloro-phenyl)-ethyl]-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 101910-04-7 (Z)-(3R,5R)-7-(2,4-Dichloro-phenyl)-1-phenylsulfanyl-hept-1-ene-3,5-diol 
• 90761-31-2 7-(2,4-Dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide 
• 130217-65-1 (E)-1-(2,4-dichlorophenyl)-2-(3,4-dichlorophenyl)ethene 
• 1258606-08-4 (E)-1-(2,4-dichlorophenyl)-2-(3-chlorophenyl)ethene 
• 51042-15-0 trans-2,2',4,4'-tetrachlorostilbene 

Relevant academic research and scientific papers

Synthesis and biological evaluation of some stilbene-based analogues

The phytoalexin 3,5,40-trihydroxy-trans-stilbene (resveratrol) has attracted considerable attention from biologists and chemists due to its diverse biological properties. Owing to the biological importance of this compound, we have synthesized new stilbene-based analogues by using substituted benzyl chlorides and substituted aldehydes in a two-step reaction and evaluated their in vitro antioxidant, antibacterial and antifungal potential. Most of the compounds displayed moderate to significant radical scavenging activity. (E)-1-(3,4-difluorophenyl)-2-(4-fluorophenyl) ethene (4c) showed nearer equipotent antibacterial activity against Staphylococcus aureus. (E)-1,2-bis (4-fluorophenyl)ethene (4a), (E)-1-(3-fluorophenyl)-2-(4-fluorophenyl)ethene (4b), (E)-1-(2,4-dichlorophenyl)-2-(3, 4-dichlorophenyl)ethene (4f), (E)-1-(2,4-dichlorophenyl)-2-(3-chlorophenyl)ethene (4g), (E)-1-(2,4- dichlorophenyl)-2-(4-fluorophenyl)ethene (4j) (E)-1-(4-fluorophenyl)-2-(3- chlorophenyl)ethene (4l) and (E)-1-(4-chlorophenyl)-2-(4-fluorophenyl)ethene (4n) inhibited the growth of Penicillium chrysogenum. Springer Science+Business Media, LLC 2010.

Syntheses of 2-(2-arylethyl)-1-methylimidazoles

2-(2-Arylethyl)-1-methylimidazoles 3 could be prepared by different methods. The best method was the Wittig reaction of aryltriphenylphosphonium chloride 8 with 2-formyl-1-methylimidazole to give compound 6. Reduction of compound 6 with Raney nickel gave compound 3.