24949-44-8

Usage

Uses

Used in Pharmaceutical Development:
(3Z)-3-(2-oxopropylidene)-3,4-dihydroquinoxalin-2(1H)-one is used as a potential pharmaceutical candidate due to the biological activities associated with quinoxaline compounds. Its specific role in medicine may be determined through further research, but it could contribute to the development of new drugs targeting various diseases and conditions.
Used in Agrochemical Research:
In the field of agriculture, (3Z)-3-(2-oxopropylidene)-3,4-dihydroquinoxalin-2(1H)-one may be utilized as a component in the development of agrochemicals. Its potential applications could include the creation of pesticides, herbicides, or other agricultural chemicals that leverage the compound's biological properties to control pests or enhance crop growth.
Used in Material Science:
(3Z)-3-(2-oxopropylidene)-3,4-dihydroquinoxalin-2(1H)-one may also find applications in material science. (3Z)-3-(2-oxopropylidene)-3,4-dihydroquinoxalin-2(1H)-one's unique structure and properties could be harnessed to develop new materials with specific characteristics, such as improved conductivity, stability, or reactivity, depending on the needs of various industries.

Upstream product

• 53120-38-0 2-hydroxy-4-oxopent-2-enoic acid ethyl ester 
• 95-54-5 1,2-diamino-benzene 
• 95-92-1 oxalic acid diethyl ester 
• 67-64-1 acetone 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 

Relevant academic research and scientific papers

Simple procedure for preparation of quinoxalin-2(1H)-one 3-[oxo(cyclo)alkyl(idene)] derivatives

A simple preparative procedure was developed for 3-(2-oxoalkylidene)-3,4- dihydroquinoxalin-2(1H)-ones, 4,5-dihydroxy-1-[3-oxo-3,4-dihydroquinoxalin-2(1H) -ylidene]-3,5-octadiene-2,7-dione, and 3-(2,3-dihydroxy-4-methyl-5-oxo-1,3- cyclopentadien-1-yl)quinoxalin-2(1H)-one by reaction of methyl ketones first with diethyl oxalate in the presence of sodium, and then with o-phenylenediamine.

Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis

Herein, a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated. A wide range of functional groups are compatible, affording the corresponding products in moderate-to-good yields. Control experiments illustrate that the in situ generated 1O2 plays a central role in this reaction. This green and efficient strategy provides a practical solution for the synthesis of potentially bioactive compounds that containing a 3,4-dihydroquinoxalin-2(1H)-one structure.

REACTION OF POLYFLUOROACYLPYRUVIC ESTERS WITH N-DINUCLEOPHILES

According to the 13C NMR spectra, polyfluoroacylpyruvic esters are enolized at the carbonyl carbon atom attached to the ester group. The reaction of these compounds with ethylenediamine (o-phenylenediamine) takes place at the α-keto ester fragment of the