249516-40-3

Upstream product

• 96447-49-3 4-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)thiosemicarbazide 
• 104-55-2 3-phenyl-propenal 
• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 

Relevant academic research and scientific papers

Synthesis and antiinflammatory activity of novel 3-(2,3-dimethyl-1-phenyl-4-pyrazolon-5-yl)-4-thiazolidiones

New 3-(2,3-dimethyl-1-phenyl-4-pyrazolon-5-yl)-4-thiazolidines were synthesized. The structure of substances was supported by UV- and 1H-NMR spectra. Some compounds were tested in vivo for their antiinflammatory activity. Were confirmed previous results about structure-activity relationships.

New thiazolidones-4 with pyrazolone-5 substituent as the potential NSAIDs

The synthesis of a group of thiazolidine derivatives with pyrazolone-5 substituent is described. The structure of the new compounds is supported by 1H- and 13C-NMR spectra. Group of compounds was tested in vivo for their antiinflammatory activity. The obtained results gave the opportunity to separate the perspective groups of potential NSAIDs, which have got greater antiinflammatory activity than the best standard drugs.