24959-64-6

Basic information

• Product Name: Benzene, 1-chloro-3-[2-(4-fluorophenyl)ethenyl]-, (E)-
• CAS NO: 24959-64-6
• Molecular Formula: C14H10ClF
• Molecular Weight: 232.685
• Mol File: 24959-64-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-3-[2-(4-fluorophenyl)ethenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-3-[2-(4-fluorophenyl)ethenyl]-, (E)-(24959-64-6)
• EPA Substance Registry System: Benzene, 1-chloro-3-[2-(4-fluorophenyl)ethenyl]-, (E)-(24959-64-6)

Safety Data

• Hazardous Substances Data: 24959-64-6(Hazardous Substances Data)

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 459-46-1 4-Fluorobenzyl bromide 
• 3462-95-1 (4-fluorobenzyl)triphenylphosphonium chloride 
• 603-35-0 triphenylphosphine 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 133472-26-1 (3-chlorophenyl)zinc(II) chloride 
• 405-99-2 para-fluorostyrene 

Downstream Products

• 24941-75-1 4-Fluor-3'-chlorbibenzyl 

Relevant articles and documents

An Interrupted Pummerer/Nickel-Catalysed Cross-Coupling Sequence

An interrupted Pummerer/nickel-catalysed cross-coupling strategy has been developed and used in the elaboration of styrenes. The operationally simple method can be carried out as a one-pot process, involves the direct formation of stable alkenyl sulfonium salt intermediates, utilises a commercially available sulfoxide, catalyst, and ligand, operates at ambient temperature, accommodates sp-, sp2-, and sp3-hybridised organozinc coupling partners, and delivers functionalised styrene products in high yields over two steps. An interrupted Pummerer/cyclisation approach has also been used to access carbo- and heterocyclic alkenyl sulfonium salts for cross-coupling.