24974-74-1

Basic information

• Product Name: 2-BROMOBENZYLSULFONYL CHLORIDE
• Synonyms: 2-BROMOBENZYLSULFONYL CHLORIDE;(2-Bromophenyl)methanesulphonyl chloride;(2-Bromophenyl)methanesulphonyl chloride 97%;2-Bromobenzylsulphonyl chloride;2-Bromobenzylsulphonyl chloride 97%;(2-broMophenyl)Methanesulfonyl chloride
• CAS NO: 24974-74-1
• Molecular Formula: C₇H₆BrClO₂S
• Molecular Weight: 269.54
• Mol File: 24974-74-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 78 °C
• Boiling Point: 345.2 °C at 760 mmHg
• Flash Point: 162.6 °C
• Appearance: /
• Density: 1.746 g/cm³
• Vapor Pressure: 0.000125mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-BROMOBENZYLSULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOBENZYLSULFONYL CHLORIDE(24974-74-1)
• EPA Substance Registry System: 2-BROMOBENZYLSULFONYL CHLORIDE(24974-74-1)

Safety Data

• Hazard Codes: C,Xn
• Statements: 22
• Hazardous Substances Data: 24974-74-1(Hazardous Substances Data)

Usage

General Description

2-Bromobenzylsulfonyl Chloride is a chemical compound often used in scientific research as a reagent. This organic compound is notable for its bromine and sulfur constituents, which contribute to its unique reactivity. It engages in various chemical reactions, specifically serving as a sulfur-based electrophile that allows it to interact with other molecules in a manner that facilitates the formation of organic sulfonyl structures. It is not naturally occurring and must be synthesized in a laboratory setting, often through complex chemical procedures. As with many chemicals, appropriate safety measures should be taken to avoid exposure due to its potential corrosiveness and other hazardous effects. The exact properties, such as its melting point, boiling point, and density, can vary based on its exact formulation and purity. It is sold by various chemical supply companies for use in research and development.

InChI:InChI=1/C7H6BrClO2S/c8-7-4-2-1-3-6(7)5-12(9,10)11/h1-4H,5H2

Upstream product

• 578-51-8 2-bromobenzylchloride 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 1298109-31-5 C₁₈H₁₃BrF₅NO₄S 
• 1298109-20-2 C₁₃H₇BrF₅NO₂S 
• 1418201-73-6 1-(2-bromophenyl)-N-(2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)benzyl)methanesulfonamide 

Relevant articles and documents

Rhodium-Catalyzed meta-C?H Functionalization of Arenes

Rhodium-catalyzed ortho-C?H functionalization is well known in the literature. Described herein is the Xphos-supported rhodium catalysis of meta-C?H olefination of benzylsulfonic acid and phenyl acetic acid frameworks with the assistance of a para-methoxy-substituted cyano phenol as the directing group. Complete mono-selectivity is observed for both scaffolds. A wide range of olefins and functional groups attached to arene are tolerated in this protocol.