249741-59-1Relevant academic research and scientific papers
Apoptosis-inducing compounds
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, (2008/06/13)
The present invention relates to pyrrolobenzoxazepines, pyrrolobenzthiazepines and related compounds having the ability to induce apoptosis, to pharmaceutical compositions comprising these compounds and to their use as anti-tumour agents.
Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR)
Campiani, Giuseppe,Ramunno, Anna,Fiorini, Isabella,Nacci, Vito,Morelli, Elena,Novellino, Ettore,Goegan, Mara,Mennini, Tiziana,Sullivan, Stephen,Zisterer, Daniela M.,Williams, Clive D.
, p. 4276 - 4281 (2007/10/03)
In the present study, we have synthesized and tested novel pyridopyrrolo- and pyrrolobenzoxazepine derivatives, as novel and selective peripheral type benzodiazepine receptor (PBR) ligands, and their ability to modulate steroid biosynthesis has been inves
