249745-72-0

Upstream product

• 542-69-8 1-iodo-butane 
• 192060-67-6 (1R,2R)-(-)-pseudoephedrinepropionamide 
• 109-65-9 1-bromo-butane 
• 321-97-1 (1R,2R)-pseudoephedrine 

Downstream Products

• 249745-85-5 (2S,4S)-N-[(1R,2R)-2-hydroxy-1-methyl-2-phenylethyl]-N,2,4-trimethyloctanamide 
• 249745-79-7 (2R,4S)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2,4-trimethyloctanamide 
• 624-22-6 (2S)-2-methyl-1-hexanol 

Relevant academic research and scientific papers

Disodium Salts of Pseudoephedrine-Derived Myers Enolates: Stereoselectivity and Mechanism of Alkylation

Pseudoephedrine-derived dianionic Myers enolates were generated using sodium diisopropylamide (NaDA) in THF solution. The reactivities and selectivities of the disodium salts largely mirror those of the dilithium salts but without the requisite large exce

Sex pheromone of the pine sawfly, Macrodiprion nemoralis. Stereoselective synthesis of the sixteen stereoisomers of 3,7,9-trimethyl-2-tridecyl acetate

The sixteen stereoisomers of 3,7,9-trimethyl-2-tridecyl acetate (5Ac) were prepared individually, each in over 99.5% stereochemical purity. The syntheses were based on the ring opening of a pure enantiomer of cis-3,4-dimethyl-γ-butyrolactone using a pure stereoisomer of 1-lithio-2,4-dimethyloctane, the two stereogenic centres of which were introduced with high selectivity by alkylations of the amide enolates from the appropriate enantiomers of pseudoephedrine. (2S,3R,7R,9S)-3,7,9-Trimethyl-2-tridecyl acetate (SRRS-5Ac) has recently been found to be the major component of the female sex pheromone of Macrodiprion nemoralis (Hymenoptera: Diprionidae). A synthetic method for the preparation of a sixteen isomer mixture of 5Ac is also presented. This mixture has been found to be biologically active in field tests.