249930-46-9Relevant articles and documents
4-AMINO OR 4-ALKOXY-SUBSTITUTED ARYL SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS
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, (2020/07/05)
Disclosed are compounds of Formula (I), Formula (II), or a salt thereof: Formula (I) Formula (II) which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (I), Formula (II) or their salts, and methods of treating pain disorders, cough, and itch using the same.
Stereoselective total synthesis of (±)-fragranol by TiCl4 promoted [2 + 2] cycloaddition of allyl-tert-butyldiphenylsilane and methyl methacrylate
Knoelker, Hans-Joachim,Baum, Gerhard,Schmitt, Oliver,Wanzl, Guenter
, p. 1737 - 1738 (2007/10/03)
A stereoselective total synthesis of the monoterpenoid alcohol (±)-fragranol has been accomplished utilizing a TiCl4 promoted [2 ± 2] cycloaddition of allyl-tert-butyldiphenylsilane and methyl methacrylate as the key step.