249931-49-5

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 249931-50-8 (-)-(S_S)-5,7-dimethoxy-8-methyl-3-(p-tolylsulfinyl)chromen-4-one 
• 14107-97-2 2,4,6-trimethoxytoluene 
• 249931-48-4 (-)-(R_S)-1-(2-hydroxy-4,6-dimethoxy-3-methylphenyl)-2-(p-tolylsulfinyl)ethanone 
• 249931-47-3 (R_S)-1-(2-hydroxy-4,6-dimethoxy-3-methylphenyl)-2-(p-tolylsulfinyl)ethanol 
• 50827-65-1 2-hydroxy-4,6-dimethoxy-3-methylbenzaldehyde 
• 81574-58-5 2,4,6-trimethoxy-3-methylbenzaldehyde 

Downstream Products

• 249931-52-0 (+)-(R)-5-hydroxy-7-methoxy-8-methylflavanone 
• 249931-51-9 (+)-(R)-dimethylcryptostrobin 

Relevant academic research and scientific papers

Synthesis of (+)-(R)-5-hydroxy-6-hydroxymethyl-7-methoxy-8-methylflavanone

The synthesis of (+)-(R)-5-hydroxy-6-hydroxymethyl-7-methoxy-8-methylflavanone is described. A new chromylation method of β-ketosulfoxide 9 leading to the Michael acceptor 12 has been developed. Dilithium tetra-chlorocuprate was shown to be a very efficie