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2,3-BIS-(2'-PYRIDYL)-5,6-DIHYDROPYRAZINE, a heterocyclic compound with the molecular formula C16H16N4, features two pyridine rings and a dihydropyrazine ring. It is utilized in the pharmaceutical industry as a key building block for the synthesis of a variety of drug molecules. Its unique structural and functional properties have also made it a valuable research tool in chemical and biological studies, with potential pharmacological activities that include applications in treating cancer and neurological disorders.

25005-95-2

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25005-95-2 Usage

Uses

Used in Pharmaceutical Industry:
2,3-BIS-(2'-PYRIDYL)-5,6-DIHYDROPYRAZINE is used as a building block for the synthesis of drug molecules due to its versatile chemical structure and potential to contribute to the development of new therapeutic agents.
Used in Cancer Treatment Research:
In the field of oncology, 2,3-BIS-(2'-PYRIDYL)-5,6-DIHYDROPYRAZINE is studied for its potential role in the treatment of cancer, given its pharmacological properties that may target and combat cancer cells.
Used in Neurological Disorder Research:
2,3-BIS-(2'-PYRIDYL)-5,6-DIHYDROPYRAZINE is also being investigated for its possible applications in the treatment of neurological disorders, leveraging its capacity to interact with biological systems at the molecular level.
Used as a Research Tool in Chemical and Biological Studies:
2,3-BIS-(2'-PYRIDYL)-5,6-DIHYDROPYRAZINE serves as a research tool in chemical and biological studies, enabling scientists to explore its unique structural and functional attributes for potential applications in various scientific and medical fields.

Check Digit Verification of cas no

The CAS Registry Mumber 25005-95-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,0,0 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25005-95:
(7*2)+(6*5)+(5*0)+(4*0)+(3*5)+(2*9)+(1*5)=82
82 % 10 = 2
So 25005-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H12N4/c1-3-7-15-11(5-1)13-14(18-10-9-17-13)12-6-2-4-8-16-12/h1-8H,9-10H2

25005-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,6-dipyridin-2-yl-2,3-dihydropyrazine

1.2 Other means of identification

Product number -
Other names Pyrazine,2,3-dihydro-5,6-di-2-pyridinyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:25005-95-2 SDS

25005-95-2Downstream Products

25005-95-2Relevant academic research and scientific papers

Palladium(II) and Platinum(II) Mononuclear Complexes and Tendency to Undergo Dehydrogenation of the Multiple N-Donor Ligand Di-(2-pyridyl)dihydropyrazine

Raciti, Edoardo,Donzello, Maria Pia,Viola, Elisa,Bassetti, Mauro,Pettiti, Ida,Bellucci, Noemi,Rizzoli, Corrado,Ercolani, Claudio

, p. 8893 - 8905 (2020)

The already known di(2-pyridyl)dihydropyrazine (dhdpp) was prepared and isolated also in the form of a bis-hydrated species, i.e., dhdpp·2H2O. As established by X-ray work, a small amount of single crystals of di(2-pyridyl)-pyrazine (dpp) was also obtained from the mother liquors, this testifying the possibility of a dehydrogenation process dhdpp → dpp in the absence of a catalyst. Using dhdpp as a ligand, mononuclear metal derivatives of formula [(dhdpp)MCl2]·xH2O (M = PdII, PtII) were obtained as stable-to-air solids, studied by X-ray powder, IR, UV-visible, and 1H NMR spectra, and proved to exhibit a N2MCl2 coordination site involving one pyridine and one pyrazine N atom ("py-pyz"coordination). An interesting relationship has been established in terms of the observed types of coordination with the analogs of di(2-pyridyl)-pyrazine (dpp) formulated as [(dpp)MCl2]·3H2O, proved also by 1H NMR spectra to exhibit the "py-pyz"mode of coordination. Attempts to isolate from the reaction of dhdpp with Pd(OAc)2 the corresponding mononuclear derivatives were shown to lead, as definitely supported by 1H NMR spectral data and crystallographic work, to the exclusive formation of the corresponding dpp complex [(dpp)Pd(OAc)2]·5H2O ("py-pyz"coordination site), this proving the tendency of dhdpp to generate dpp under different reaction conditions. The promoted conversion of dhdpp into dpp in the complex was examined by sequential NMR analysis and established to be determined by Pd(OAc)2 which plays the role of catalyst. The new salt-like species [(CH3)(dhdpp)PdI2](I)·7H2O, prepared starting from [(dhdpp)PdCl2] in its reaction with CH3I, allowed the separation from the mother liquors of small brown crystals identified on the basis of X-ray analysis as the already known complex of formula [(dpp)PdI2] ("py-py"coordination), this result once again outlining the tendency of dhdpp to be dehydrogenated to dpp.

Ru(ii) water oxidation catalysts with 2,3-bis(2-pyridyl)pyrazine and tris(pyrazolyl)methane ligands: Assembly of photo-active and catalytically active subunits in a dinuclear structure

Bortoluzzi, Marco,Campagna, Sebastiano,De Palo, Alice,Guelfi, Massimo,La Ganga, Giuseppina,Marchetti, Fabio,Nastasi, Francesco,Pampaloni, Guido,Puntoriero, Fausto

, p. 3341 - 3352 (2020/03/19)

Two mononuclear Ru(ii) complexes, i.e. [RuCl(κ3N-terpy)(κ2N-dpp)]PF6 ([1]PF6; terpy = 2,2′:6′,2′′-terpyridine; dpp = 2,3-bis(2′-pyridyl-pyrazine) and [RuCl(κ3N-tpm)(κ2N-dpp)]Cl ([2]Cl; tpm = tris(1-pyrazolyl)methane), and one dinuclear complex, i.e. [Ru2Cl(κ3N-tpm)(μ-κ2N:κ2N-dpp)Ru(κ2N-bpy)2][PF6]3 ([3][PF6]3; bpy = 2,2′-bipyridine), have been synthesized and their water oxidation catalytic properties have been investigated. A combined DFT and experimental (35Cl NMR and conductivity measurements) study aimed to elucidate the nature of [1]+ and [2]+ in aqueous solution has also been performed, indicating that one water molecule is allowed to enter the first coordination sphere of [2]+ in the ground state, replacing one tpm nitrogen. Conversely, in the case of [1]+, water coordination, assumed to be needed for the water oxidation process, presumably occurs following the oxidation of the metal. For all complexes, a catalytic wave has been detected in acetonitrile/water 1 : 1 (v/v) solution in the range 1.4-1.7 V vs. SCE. In all cases, water oxidation (investigated at pH -1, respectively) of the complexes are higher than those of the benchmark [Ru(LLL)(LL)(OH2)]2+-type species (LLL and LL are tridentate and bidentate polypyridine ligands, respectively), which is [Ru(terpy)(bpm)(OH2)]2+.

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