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4-methyl-N-[(1E)-(6-nitro-1,3-benzodioxol-5-yl)methylene]aniline is a complex organic compound characterized by a 4-methylaniline group connected to a 6-nitro-1,3-benzodioxole moiety through a methylene bridge in the E configuration. This molecule features a nitro group at the 6-position of the benzodioxole ring, which imparts specific electronic and steric properties. The compound is of interest in chemical research due to its potential applications in the synthesis of pharmaceuticals and other specialty chemicals, where its unique structure may confer specific biological activities or reactivity.

2501-04-4

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2501-04-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2501-04-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,0 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2501-04:
(6*2)+(5*5)+(4*0)+(3*1)+(2*0)+(1*4)=44
44 % 10 = 4
So 2501-04-4 is a valid CAS Registry Number.

2501-04-4Relevant academic research and scientific papers

Synthesis and bioevaluation of 22-hydroxyacuminatine analogs

Grillet, Francois,Baumlova, Barbora,Prevost, Gregoire,Constant, Jean-Francois,Chaumeron, Sophie,Bigg, Dennis C.H.,Greene, Andrew E.,Kanazawa, Alice

, p. 2143 - 2146 (2008)

A series of 22-hydroxyacuminatine analogs was prepared by using different Friedlaender condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedl?nder reaction

Gavara, Laurent,Boisse, Thomas,Hénichart, Jean-Pierre,Da?ch, Adam,Rigo, Beno?t,Gautret, Philippe

experimental part, p. 7544 - 7561 (2010/12/25)

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedl?nder condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.

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