25016-12-0Relevant articles and documents
Method for synthesizing 1,3-dimethyl-1H-pyrazole-4-carboxylic acid
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Paragraph 0020; 0035; 0038; 0052-0057, (2019/11/12)
The invention relates to a method for synthesizing 1,3-dimethyl-1H-pyrazole-4-carboxylic acid. The method comprises the step that 1,3-dimethyl-1H-pyrazole-4-carboxylic acid is prepared from the raw material: ethyl acetoacetate through condensation and ring closure, formylation, reductive dechlorination and oxidation. Compared with an existing method, the method has lower reaction cost, a higher yield and better economic performance; and the problems such as cost and environmental pollution caused by heavy metal oxidation are solved, and conditions are created for industrialization.