250586-06-2Relevant academic research and scientific papers
New efficient synthesis of (3R,4S)-3-methyl-3-hydroxy-4-phenyl-β-lactam
Barbaro, Gaetano,Battaglia, Arturo,Di Giuseppe, Fabio,Giorgianni, Patrizia,Guerrini, Andrea,Bertucci, Carlo,Geremia, Silvano
, p. 2765 - 2773 (2007/10/03)
A method is described for the chiral synthesis of (3R,4S)-3-methyl-3-hydroxy-4-phenyl-β-lactam, a useful precursor for the semi-synthesis of 2'-methyl-taxoids. This protocol follows Seebach's synthetic principle of 'self-regeneration of stereocenters' (SR
