209110-60-1

Upstream product

• 209110-55-4 (3R,4S)-3-(Dimethyl-phenyl-silanyloxy)-1-(4-methoxy-phenyl)-3-methyl-4-phenyl-azetidin-2-one 
• 209110-50-9 (3R,4S)-3-(Dimethyl-phenyl-silanyloxy)-1-(4-methoxy-phenyl)-4-phenyl-azetidin-2-one 
• 768-33-2 phenyldimethylsilyl chloride 
• 144465-78-1 1-(4-Methoxyphenyl)-3-triisopropylsilyloxy-4-phenyl-2-azetidinone 
• 250586-06-2 (1'S,2S,5R)-2-(tert-butyl)-5-(1'-amino-1'-phenylmethyl)-5-methyl-1,3-dioxolan-4-one 
• 182155-36-8 (3R,4S)-3-hydroxy-3-methyl-4-phenyl-β-lactam 

Downstream Products

• 209110-70-3 (3R,4S)-3-(Dimethyl-phenyl-silanyloxy)-3-methyl-2-oxo-4-phenyl-azetidine-1-carboxylic acid tert-butyl ester 
• 168416-37-3 (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-2-methyl-3-phenylpropionic acid methyl ester 

Relevant academic research and scientific papers

New efficient synthesis of (3R,4S)-3-methyl-3-hydroxy-4-phenyl-β-lactam

A method is described for the chiral synthesis of (3R,4S)-3-methyl-3-hydroxy-4-phenyl-β-lactam, a useful precursor for the semi-synthesis of 2'-methyl-taxoids. This protocol follows Seebach's synthetic principle of 'self-regeneration of stereocenters' (SR

Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.