250586-16-4

Upstream product

• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 619261-61-9 (Z)-2-ethyl-3-phenylnon-2-en-4-yn-1-ol 
• 1585185-69-8 C₂₂H₂₅NO₃S 
• 1585185-90-5 C₂₁H₂₂INO₂S 
• 1585185-83-6 C₂₁H₂₂INO₂S 
• 1394159-26-2 C₂₅H₃₁NO₄S 
• 1350809-93-6 C₁₄H₁₈INO₂ 
• 1350809-90-3 C₂₁H₂₅IN₂O₃S 
• 1350810-31-9 C₁₃H₁₅IO₂ 
• 1350810-27-3 C₂₀H₂₂INO₃S 
• 1350810-21-7 C₂₄H₃₂INO₄S 
• 1350810-11-5 C₁₃H₁₃NO 
• 1350810-04-6 C₁₄H₁₇NO₂ 
• 1350810-10-4 C₂₀H₂₁NO₃S 
• 1350810-01-3 C₂₁H₂₄N₂O₃S 

Relevant academic research and scientific papers

Regioselective Synthesis of 5-Metalated 2-Pyrones by Intramolecular Oxymetalation of Carbonyl-ene-yne Compounds Using Indium Trihalide

The oxyindation of carbonyl-ene-yne compounds with indium trihalides proceeded efficiently to give di-, tri-, and tetrasubstituted 2-pyrones bearing a carbon-indium bond. The metalated 2-pyrone and a zwitterion intermediate were identified by X-ray crystallographic analysis. The application of organoindium compounds to oxidation or cross-coupling provided easy access to various multifunctionalized 2-pyrones. Some 2-pyrone derivatives show intense fluorescence only in the solid state (aggregation-induced emission).

Palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide

This Letter describes a palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide in the presence of alkylol, which provides a facile access to 2-alkoxy-3-methylene-tetrahydropyridine. The asymmetric version of this reaction has also been preliminarily realized with up to 81% enantioselectivity when chiral bisphosphine ligands were used.

Synthesis of 3-pyrroline via domino Heck-aza-Michael reaction

This Letter describes the Pd(0)-catalyzed domino Heck-aza-Michael reaction between (Z)-N-(3-iodoallyl)-tosylamide and acrylic ester. The reaction provides a facile access to an important class of substituted 3-pyrroline.

Palladium-catalyzed Heck-type reaction of oxime ether bearing a pendant vinyl iodide moiety

A Pd(0)-catalyzed intramolecular Heck-type reaction of oxime ether has been developed, providing convenient access to heterocyclic oximes. The Royal Society of Chemistry 2011.

General and regioselective synthesis of substituted pyrroles by metal-catalyzed or spontaneous cycloisomerization of (Z)-(2-en-4-ynyl)amines

A general and regioselective synthesis of substituted pyrroles 2 by cycloisomerization of readily available (Z)-(2-en-4-ynyl)amines 1 is reported. Spontaneous cycloisomerization leading to 2 occurred in the course of preparation of enynamines bearing a terminal triple bond or a triple bond substituted with a phenyl or a CH2OTHP group. When the triple bond was substituted with an alkyl or alkenyl group, enynamines were stable and could be converted into the corresponding pyrroles by metal catalysis. CuCl 2 was found to be an excellent catalyst for cycloisomerization of substrates substituted at C-3, while PdX2 in conjunction with KX (X = Cl, I) turned out to be a superior catalyst for the reaction of enynamines unsubstituted at C-3.