2506-48-1Relevant academic research and scientific papers
Cobalt(II) chloride hexahydrate-diisopropylamine catalyzed mild and chemoselective reduction of carboxylic esters with sodium borohydride
Jagdale, Arun R.,Paraskar, Abhimanyu S.,Sudalai, Arumugam
experimental part, p. 660 - 664 (2009/07/03)
The cobalt-catalyzed reduction of unsaturated α-cyano carboxylic esters using sodium borohydride (NaBH4) leads to the corresponding saturated cyano alcohols in high yields. In particular, the new catalytic system cobalt(II) chloride-diisopropylamine in combination with NaBH4 showed excellent activity in the chemoselective reduction of a variety of carboxylic esters to their corresponding alcohols in good to excellent yields under mild conditions. Georg Thieme Verlag Stuttgart.
