250699-41-3

Basic information

• Product Name: 5-phenyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione
• Synonyms: 5-phenyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione
• CAS NO: 250699-41-3
• Molecular Weight: 296.349
• Mol File: 250699-41-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-phenyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(250699-41-3)
• EPA Substance Registry System: 5-phenyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(250699-41-3)

Safety Data

• Hazardous Substances Data: 250699-41-3(Hazardous Substances Data)

Upstream product

• 197368-44-8 Co 102581 
• 6006-82-2 3,4-methylenedioxyphenethyl alcohol 
• 132813-86-6 2-Benzoyl-4,5-methylenedioxyphenylacetic acid 
• 2861-28-1 1,3-benzodioxole-5-acetic acid 
• 53616-33-4 5-phenyl-1,3-dioxolo[4,5-g]isochromane 

Downstream Products

• 862457-85-0 (2-methyl[1,3]dioxolan-2-ylmethyl)-(5-phenyl-7,9-dihydro-1,3-dioxa-6,7-diazacyclohepta[f]inden-8-ylidene)amine 
• 194730-09-1 5-phenyl-8-methyl-11H-1,3-dioxolo[4,5-h]imidazo[1,2-c][2,3]benzodiazepine 

Relevant articles and documents

Novel α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: Chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration

Under pathophysiological conditions, α-amino-3-hydroxy-5-methyl-4- isoxazole propionate (AMPA) receptor activation is considered to play a key role in several disorders of the central nervous system. In the search for AMPA receptor antagonists, the synthe

Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists

We have previously shown that 1-aryl-3,5-dihydro-7,8-methylenedioxy-4H- 2,3-benzodiazepin-4-ones (3) possess marked anticonvulsant properties and antagonize seizures induced by 2-amino-3-(3-hydroxy-5-methylisoxazol-4- yl)propionic acid (AMPA) in analogy t