25105-56-0Relevant academic research and scientific papers
Solution-phase parallel synthesis of novel 1,2,3,4-tetrahydroisoquinolin-1- ones as anticonvulsant agents
Gitto, Rosaria,Francica, Eleonora,De Sarro, Giovambattista,Scicchitano, Francesca,Chimirri, Alba
, p. 181 - 184 (2008)
Following our previous studies in the field of anticonvulsant agents, we planned a one-pot solution-phase parallel synthesis (SPPS) of a small library of new 1,2,3,4-tetrahydroisoquinoline derivatives. The activity against audiogenic seizures in DBA/2 mice of the newly synthesized compounds has also been evaluated.
