25112-86-1

Usage

InChI:InChI=1/C8H12O2/c1-3-10-8-5-4-7(9)6(8)2/h3-5H2,1-2H3

Upstream product

• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 64-17-5 ethanol 
• 5870-63-3 3-hydroxy-2-methyl-2-cyclopenten-1-one 
• 75-03-6 ethyl iodide 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 54158-61-1 2-methyl-3-(4-methylphenyl)-2-cyclopentenone 
• 26029-34-5 2-methyl-3-phenyl-2-cyclopentenone 
• 4608-44-0 2,3-dimethyl-3-(p-tolyl)cyclopentan-1-one 
• 2819-12-7 3-(phenylthio)-2-methylcyclopentanone 

Relevant academic research and scientific papers

AN INTRAMOLECULAR CYCLOADDITION-SIGMATROPIC REARRANGEMENT APPROACH TO (+/-) GASCARDIC ACID

A general intramolecular Diels-Alder:anionic oxy-Cope strategy for the synthesis of tricyclic skeletons and its application to the preparation of the gascardic acid precursor 12 is described.In situ generation of the appropriate cyclopentadiene 5 by isomerization (Et3N) afforded the adduct directly or with EtAlCl2 as catalyst.The requisite potassium salt of the 1,5 diene 10 rearranged at 67 deg C to the fused ring ketone 11.Selecvtive allylic oxidation and reduction provided 12.

2-methylcyclopentane-1,3-dione: An efficient synthon for the synthesis of (±)-α-cuparenone

A very short and efficient synthesis of (±)-α-cuparenone was achieved in 4 steps from 2-methylcyclopentane-1,3-dione.

A New Approach to Hydroazulenes via Olefin Metathesis

Several functionalized diolefins cyclize to hydroazulenes (among others) via olefin metathesis with CH3ReO3.These conversions are regioselective and occur with high diastereoselectivity.

The synthesis of trisubstituted cyclopentadienes and their reactivity in the intramolecular Diels-Alder reaction

The intramolecular Diels-Alder reactivity of several trisubstituted cyclopentadienes is described and a general method for their preparation reported.In general, sidechain keto-ester functionality has an adverse effect on these internal cycloadditions.

2,2-DISUBSTITUIERTE CYCLOPENTAN-1,3-DIONE-21. UNTERSUCHUNG DER REGIOSELEKTIVITAET VON ALKYLIERUNGSREAKTIONEN AN 2-METHYL-CYCLOPENTAN-1,3-DION

The regioselectivity of the alkylation of alkali metal salts of 2-methyl-cyclopentane-1,3-dione with alkyl halides depends significantly on the structure of the alkylating reagent and the type of solvent used in the reaction.Unsubstituted saturated primar