25112-86-1Relevant articles and documents
AN INTRAMOLECULAR CYCLOADDITION-SIGMATROPIC REARRANGEMENT APPROACH TO (+/-) GASCARDIC ACID
Berube, Gervais,Fallis, Alex G.
, p. 4045 - 4048 (1989)
A general intramolecular Diels-Alder:anionic oxy-Cope strategy for the synthesis of tricyclic skeletons and its application to the preparation of the gascardic acid precursor 12 is described.In situ generation of the appropriate cyclopentadiene 5 by isomerization (Et3N) afforded the adduct directly or with EtAlCl2 as catalyst.The requisite potassium salt of the 1,5 diene 10 rearranged at 67 deg C to the fused ring ketone 11.Selecvtive allylic oxidation and reduction provided 12.
A New Approach to Hydroazulenes via Olefin Metathesis
Junga, Heiko,Blechert, Siegfried
, p. 3731 - 3732 (2007/10/02)
Several functionalized diolefins cyclize to hydroazulenes (among others) via olefin metathesis with CH3ReO3.These conversions are regioselective and occur with high diastereoselectivity.
2,2-DISUBSTITUIERTE CYCLOPENTAN-1,3-DIONE-21. UNTERSUCHUNG DER REGIOSELEKTIVITAET VON ALKYLIERUNGSREAKTIONEN AN 2-METHYL-CYCLOPENTAN-1,3-DION
Schick, Hans,Schwarz, Hartmut,Finger, Angelika,Schwarz, Sigfrid
, p. 1279 - 1283 (2007/10/02)
The regioselectivity of the alkylation of alkali metal salts of 2-methyl-cyclopentane-1,3-dione with alkyl halides depends significantly on the structure of the alkylating reagent and the type of solvent used in the reaction.Unsubstituted saturated primar