25113-57-9

Basic information

• Product Name: 2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one
• CAS NO: 25113-57-9
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.2099
• Mol File: 25113-57-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 429.5°C at 760 mmHg
• Flash Point: 213.5°C
• Density: 1.34g/cm³
• Vapor Pressure: 1.4E-07mmHg at 25°C
• Refractive Index: 1.691
• CAS DataBase Reference: 2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one(25113-57-9)
• EPA Substance Registry System: 2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one(25113-57-9)

Safety Data

• Hazardous Substances Data: 25113-57-9(Hazardous Substances Data)

Usage

Family

Isoquinolinone
Belongs to a group of chemical compounds that share a common structure and properties.

Structure

Imidazole ring fused to an isoquinoline ring
Consists of two heterocyclic rings, an imidazole and an isoquinoline, that are fused together.

Potency

Potent inhibitor of certain enzymes
Exhibits strong inhibitory effects on specific enzymes, which can be useful in medicinal applications.

Medicinal Chemistry

Potential drug development for various diseases
Due to its enzyme-inhibiting properties, it has shown promise in the development of drugs for different diseases.

Building Block

Used in the synthesis of other organic compounds
Its versatile reactivity allows it to be used as a starting material or intermediate in the synthesis of other organic compounds.

Uniqueness

Valuable in research and practical applications
The unique structure and properties of 2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one make it a valuable compound in both research and practical applications across various industries.

Upstream product

• 89-51-0 Homophthalic acid 
• 107-15-3 ethylenediamine 

Downstream Products

• 1133797-94-0 N-(3-methylphenyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinoline-10-carbothioamide 
• 1133797-92-8 N-(4-methylphenyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinoline-10-carbothioamide 
• 1133797-95-1 N-(4-methoxyphenyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinoline-10-carbothioamide 
• 1133797-91-7 N-(4-chlorophenyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinoline-10-carbothioamide 
• 1133797-97-3 N-(4-chlorobenzyl)-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinoline-10-carbothioamide 
• 1141734-74-8 N-(4-methoxyphenyl)-2-(5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinolin-10-yl)acetamide 
• 1141734-72-6 N-(4-chlorophenyl)-2-(5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinolin-10-yl)acetamide 
• 1141734-75-9 N-(4-methylphenyl)-2-(5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinolin-10-yl)acetamide 
• 1141734-77-1 2-(5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinolin-10-yl)-N-phenylacetamide 
• 1141734-67-9 10-(4-methylbenzyl)-2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one 
• 1141734-68-0 10-(4-chlorobenzyl)-2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one 
• 28670-65-7 10-benzyl-2,3-dihydroimidazo<1,2-b>isoquinolin-5(1H)-one 
• 1141734-69-1 10-(4-nitrobenzyl)-2,3-dihydroimidazo[1,2-b]isoquinolin-5(1H)-one 
• 1141734-70-4 N-(4-fluorophenyl)-2-(5-oxo-1,2,3,5-tetrahydroimidazo[1,2-b]isoquinolin-10-yl)acetamide 

Relevant articles and documents

Synthesis of 2,3-dihydroimidazo[1,2-b]isoquinoline-5(1H)-one and derivatives

A novel and efficient synthesis of 2,3-dihydroimidazo[1,2-b]isoquinoline- 5(1H)-one by microwave irradiation is reported. Several new derivatives of 2,3-dihydroimidazo[1,2-b]isoquinoline-5(1H)-one have been synthesized by acylation using DMAP as catalyst. A kinetic study employing HPLC allowed the determination of the N- and C-acylated isomers formed. Georg Thieme Verlag Stuttgart.