251306-14-6

Basic information

• Product Name: 2-(3-Hydroxypropyl)-N-[2-(3-methoxyphenyl)-ethyl]-benzoesaeureamid
• CAS NO: 251306-14-6
• Molecular Weight: 313.397
• Mol File: 251306-14-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-Hydroxypropyl)-N-[2-(3-methoxyphenyl)-ethyl]-benzoesaeureamid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Hydroxypropyl)-N-[2-(3-methoxyphenyl)-ethyl]-benzoesaeureamid(251306-14-6)
• EPA Substance Registry System: 2-(3-Hydroxypropyl)-N-[2-(3-methoxyphenyl)-ethyl]-benzoesaeureamid(251306-14-6)

Safety Data

• Hazardous Substances Data: 251306-14-6(Hazardous Substances Data)

Upstream product

• 106515-76-8 2-(3-Hydroxypropyl)benzoesaeure-methylester 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 

Relevant articles and documents

Synthesis of isoquino[1,2-a][2]benzazepines and biochemical testing of isomeric homoberbines and related papaverine-derivatives on the inhibition of phosphodiesterases

A synthesis of hitherto not accessable isoquino[1,2-a][2]benzazepines from benzoanellated seven-membered ring lactones or ε-hydroxyesters is reported; their conformation is presented. The tests of these and various similar compounds of inhibition of phosphodiesterases showed that the sterical position of one to the other benzene-ring is important. The homoberbines possess, because of their great deflexion, a weak, the norpapaverines a rather good inhibition activity: (e.g. 7, PDE III: IC50 = 1.7 μM; 8, PDE I: IC50 = 1.5 μM). For the 4,5-dihydro-3 H-2-benzazepines 13 (IC50 = 3 μM) and 14 (IC50 = 2 μM) a certain PDE IV-specifity is achieved.