251326-33-7

Upstream product

• 5159-41-1 2-iodobenzyl alcohol 
• 26260-02-6 2-iodobenzaldehyde 
• 141-43-5 ethanolamine 

Downstream Products

• 336616-83-2 3-(2-iodobenzyl)-2-methyloxazolidine-2-carboxylic acid ethyl ester 
• 1256490-82-0 3-(2-iodobenzyl)-2-(pyridin-4-yl)oxazolidine 
• 1256490-84-2 3-(2-iodobenzyl)-2-deutero-2-(pyridin-4-yl)oxazolidine 
• 1429257-06-6 4-(2-iodobenzyl)morpholin-2-one 
• 1429257-13-5 4,4′-dibenzyl-3,3′-dimethyl-3,3′-bimorpholine-2,2′-dione 
• 1066775-27-6 3,3′-dideutero-4,4′-bis(2-deuterobenzyl)-3,3′-bimorpholine-2,2′-dione 
• 1066775-01-6 4-(2-iodobenzyl)-3,3-dideuteromorpholin-2-one 
• 1429257-09-9 4,4′-dibenzyl-3,3′-bimorpholine-2,2′-dione 
• 1429257-11-3 (±)-4-(2-iodobenzyl)-3-methylmorpholin-2-one 
• 251326-37-1 4-(3-(2-iodobenzyl)-2-methyloxazolidin-2-yl)pyridine 

Relevant academic research and scientific papers

A concise method for the functionalisation of ethanolamine α to nitrogen using free radical methodology

A method is described for the free radical functionalisation of ethanolamine at the carbon atom α to nitrogen. The key step of the methodology is a 1,5-hydrogen atom abstraction to produce an α-aminoalkyl radical at C-4 of a 1,3-oxazolidine.

Free-radical functionalisation of β-amino alcohols via 1,5-hydrogen atom abstraction in 1,3-oxazolidines

Functionalisation of ethanolamine at the carbon atom α- to nitrogen can be achieved in a diastereoselective C-4 alkylation of 1,3-oxazolidines using free-radical methodology.