336616-83-2Relevant academic research and scientific papers
A concise method for the functionalisation of ethanolamine α to nitrogen using free radical methodology
Gosain, Rajendra,Norrish, Andrew M.,Wood, Mark E.
, p. 1399 - 1410 (2007/10/03)
A method is described for the free radical functionalisation of ethanolamine at the carbon atom α to nitrogen. The key step of the methodology is a 1,5-hydrogen atom abstraction to produce an α-aminoalkyl radical at C-4 of a 1,3-oxazolidine.
Free-radical functionalisation of β-amino alcohols via 1,5-hydrogen atom abstraction in 1,3-oxazolidines
Gosain, Rajendra,Norrish, Andrew M.,Wood, Mark E.
, p. 6673 - 6676 (2007/10/03)
Functionalisation of ethanolamine at the carbon atom α- to nitrogen can be achieved in a diastereoselective C-4 alkylation of 1,3-oxazolidines using free-radical methodology.
