251346-03-9

Basic information

• Product Name: 2-iodo-N-methyl-N-phenylpropanamide
• Synonyms: 2-iodo-N-methyl-N-phenylpropanamide
• CAS NO: 251346-03-9
• Molecular Weight: 289.116
• Mol File: 251346-03-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-iodo-N-methyl-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-N-methyl-N-phenylpropanamide(251346-03-9)
• EPA Substance Registry System: 2-iodo-N-methyl-N-phenylpropanamide(251346-03-9)

Safety Data

• Hazardous Substances Data: 251346-03-9(Hazardous Substances Data)

Upstream product

• 2620-11-3 2-bromo-N-methyl-N-phenylpropanamide 
• 100-61-8 N-methylaniline 

Downstream Products

• 5455-67-4 N-methyl-N-phenyl-α-hydroxypropanamide 

Relevant articles and documents

Efficient radical oxygenation of α-lodocarboxylic acid derivatives

(equation presented) Treatment of α-iodocarboxylic acid derivatives with 2 equiv of triethylborane under oxygen atmosphere gives the corresponding α-hydroxy add derivatives This method is based on an iodine atom transfer from the ethyl radical, generated by the reaction of riethylborane and oxygen, with the α-iodocarbonyl compound. It offers several advantages over classical ionic substitution reactions: no elimanation product is observed tertiary iodides are efficiently converted to alcohos, and finally, this one-step procedure is working with substrates sensitive to nucleophiles.