251346-30-2Relevant academic research and scientific papers
Efficiency of acid- and mercury-catalyzed cyclization reactions in the synthesis of tetrahydrofurans from allylsilyl alcohols
Pulido, Francisco J.,Barbero, Asuncion,Val, Patricia,Diez, Alberto,Gonzalez-Ortega, Alfonso
, p. 5350 - 5356 (2012/10/29)
The scope of the acid-catalyzed and mercury-catalyzed cyclization reactions of allylsilyl alcohols is described. This methodology has been found to be an efficient approach to the synthesis of highly substituted tetrahydrofurans. The stereoselectivity of the cyclization is dependent both on the substitution of the starting alcohol and on the catalyst. A plausible mechanism has been proposed that is consistent with the results. Copyright
Silylcuprates from allene and their reaction with α,β- unsaturatedd nitriles and imines. Synthesis of silylated oxo compounds leading to cyclopentane and cycloheptane ring formation
Barbero, Asuncion,Blanco, Yolanda,Pulido, Francisco J.
, p. 6876 - 6883 (2007/10/03)
The silylcupration of allenes and the subsequent capture of the intermediate cuprate with α,β-unsaturated nitriles is reported. The influence of the substitution of the nitrile, the nature of the silylcopper species, and the temperature on the selectivity
Allene: As small in size as versatile in synthesis. A general scope of its use-fulness as a C3-synthon for carbocyclic annulations
Barbero, Asuncion,Pulido, Francisco J.
, p. 779 - 785 (2007/10/03)
Allenes react with silylcuprates leading to allyl- or vinylsilanes depending on the structure of the allene and the nature of the silylcuprate. The silyl group used and temperature conditions can also influence the final outcome. Reversibility is a common
Acid-Catalyzed Cyclization of Epoxyallylsilanes. An Unusual Rearrangement Cyclization Process
Barbero, Asuncion,Castreno, Pilar,Pulido, Francisco J.
, p. 4045 - 4048 (2007/10/03)
(Equation presented) A new route for the synthesis of epoxyallylsilanes bearing the phenyldimethylsilyl group is reported that involves silylcupration of allene, conjugate addition to enones, and sulfur-ylide-mediated epoxidation. The Lewis acid-catalyzed
Functionalised allylsilanes from silylcopper reagents and allene. A useful strategy for cyclopentane annulations
Barbero, Asuncion,García, Carlos,Pulido, Francisco J.
, p. 2739 - 2751 (2007/10/03)
Silylcupration of allene using phenyldimethylsilylcopper or t- butyldiphenylsilylcopper followed by reaction with α,β-unsaturated acyl chlorides, aldehydes or ketones affords allylsilane-containing divinyl ketones and oxoallylsilanes, respectively. They u
Silylcupration of allenes followed by reaction with enones. A new strategy for the synthesis of methylenecyclopentanols
Barbero, Asuncion,Garcia, Carlos,Pulido, Francisco J.
, p. 6649 - 6652 (2007/10/03)
Silylcupration of allene using phenyldimethylsilyl-copper followed by conjugated addition to α,β-unsaturated ketones affords oxoallylsilanes with different substitution patterns. When the former oxoallylsilanes are treated with a Lewis acid they undergo h
