25140-95-8 Usage
General Description
2-(3-Methylphenoxy)propanoic acid, also known as Meclofenamic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and inflammation associated with various conditions such as arthritis, menstrual cramps, and minor injuries. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Meclofenamic acid is available in oral tablet form and is usually taken with food to reduce the risk of stomach upset. It should be used with caution in individuals with a history of gastrointestinal problems, as it may increase the risk of stomach bleeding and ulcers. Additionally, long-term use of this medication may increase the risk of heart attack or stroke. As with all medications, it is important to use Meclofenamic acid only as directed by a healthcare professional and to be aware of potential side effects and interactions with other drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 25140-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,1,4 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25140-95:
(7*2)+(6*5)+(5*1)+(4*4)+(3*0)+(2*9)+(1*5)=88
88 % 10 = 8
So 25140-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-7-4-3-5-9(6-7)13-8(2)10(11)12/h3-6,8H,1-2H3,(H,11,12)
25140-95-8Relevant articles and documents
Access to Optically Enriched α-Aryloxycarboxylic Esters via Carbene-Catalyzed Dynamic Kinetic Resolution and Transesterification
Liu, Bin,Song, Runjiang,Xu, Jun,Majhi, Pankaj Kumar,Yang, Xing,Yang, Song,Jin, Zhichao,Chi, Yonggui Robin
supporting information, p. 3335 - 3338 (2020/04/30)
Optically active α-aryloxycarboxylic acids and their derivatives are important functional molecules. Disclosed here is a carbene-catalyzed dynamic kinetic resolution and transesterification reaction for access to this class of molecules with up to 99% yields and 99:1 er values. Addition of a chiral carbene catalyst to the ester substrate leads to two diastereomeric azolium ester intermediates that can quickly epimerize to each other and thus allows for effective dynamic kinetic resolution to be realized. The optically enriched ester products from our reaction can be quickly transformed to chiral herbicides and other bioactive molecules.
Antiphlogistic aryloxypropionic acids: Configurational study
Azzolina,Ghislandi
, p. 713 - 724 (2007/10/02)
Configurational relationships of a series of antiphlogistic 2-aryloxypropionyl derivatives by means of 1H-NMR and HPLC methods were demonstrated. NMR spectra of racemic mixtures and optically active esters were recorded by adding suitable quant
Synthesis of (±)-marmelerin, a tetrasubstituted furanosesquiterpene
Kesavulu Reddy,Krishna Rao
, p. 372 - 375 (2007/10/02)
-
