251570-03-3Relevant articles and documents
IMIDAZOPYRIMIDINONES AND USES THEREOF
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Page/Page column 55, (2010/04/03)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
COMPOUNDS HAVING ANTIVIRAL PROPERTIES
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Page/Page column 54, (2010/04/03)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising adminis
THIAZOPYRIMIDINONES AND USES THEREOF
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Page/Page column 47-48, (2010/04/03)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising adminis
HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
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Page/Page column 114, (2008/06/13)
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula (I). Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Piperidones as tachykinin antagonists
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, (2008/06/13)
The present invention relates to a compound of the formula:- or a pharmaceutically acceptable acid addition salt or solvate thereof, wherein R is C3-C7 cycloalkyl, (C3-C7 cycloalkyl)C1-C4 alkylene or benzyl;R1 is phenyl optionally substituted by 1 or 2 su
ELECTRFLUORATION EN POSITION BENZYLIQUE DANS LE SULFOLANE
Laurent, Eliane,Marquet, Bernard,Tardivel, Robert
, p. 115 - 126 (2007/10/02)
The use of sulfolane as a solvent instead of acetonitrile in the electrofluorination of benzylic derivatives 1, (R=H, Cl) gives greater yields of benzylic fluorides 2, since the formation of acetamide byproducts 4 is prevented.However, the parallel fluorination of the aromatic nucleus is not avoided under these conditions.