25161-92-6 Usage
Uses
Used in Agricultural Applications:
(+)-Loline dihydrochloride is used as a natural defense mechanism for plants against herbivores, particularly aphids. Its presence in plants helps deter feeding and protect the plant from damage caused by these pests.
(+)-Loline dihydrochloride is also used as a protective agent for plants against environmental stresses. It aids in enhancing the plant's resilience against conditions such as drought and spatial competition, thereby improving the overall health and survival of the plant.
Used in Pharmaceutical Applications:
While not explicitly mentioned in the provided materials, due to its protective properties and interaction with biological systems, (+)-Loline dihydrochloride could potentially be investigated for its applications in the pharmaceutical industry. This may include its use in developing new drugs or therapies targeting various health conditions, leveraging its ability to protect and support the health of living organisms.
Check Digit Verification of cas no
The CAS Registry Mumber 25161-92-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,1,6 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 25161-92:
(7*2)+(6*5)+(5*1)+(4*6)+(3*1)+(2*9)+(1*2)=96
96 % 10 = 6
So 25161-92-6 is a valid CAS Registry Number.
25161-92-6Relevant academic research and scientific papers
An efficient synthesis of loline alkaloids
Cakmak, Mesut,Mayer, Peter,Trauner, Dirk
, p. 543 - 545 (2012/04/04)
Loline (1) is a small alkaloid that, in spite of its simple-looking structure, has posed surprising challenges to synthetic chemists. It has been known for more than a century and has been the subject of extensive biological investigations, but only two total syntheses have been achieved to date. Here, we report an asymmetric total synthesis of loline that, with less then ten steps, is remarkably short. Our synthesis incorporates a Sharpless epoxidation, a Grubbs olefin metathesis and an unprecedented transannular aminobromination, which converts an eight-membered cyclic carbamate into a bromopyrrolizidine. The synthesis is marked by a high degree of chemo- and stereoselectivity and gives access to several members of the loline alkaloid family. It delivers sufficient material to support a programme aimed at studying the complex interactions between plants, fungi, insects and bacteria brokered by loline alkaloids.
