25173-36-8

Usage

Uses

Used in Pharmaceutical Industry:
3-M-TOLYLOXY-PROPIONIC ACID is used as a potential active ingredient for the development of new pharmaceutical products. Its aromatic structure may allow it to interact with biological targets, making it a candidate for drug discovery and design.
Used in Dye Industry:
3-M-TOLYLOXY-PROPIONIC ACID is used as a chemical intermediate in the synthesis of dyes. Its benzene ring structure may contribute to the color properties of the dyes, making it a valuable component in the production of various dye types.
Used in Detergent Industry:
3-M-TOLYLOXY-PROPIONIC ACID is used as a raw material in the formulation of detergents. Its chemical properties may enhance the cleaning performance of detergents, contributing to their effectiveness in various cleaning applications.
Used in Polymer Industry:
3-M-TOLYLOXY-PROPIONIC ACID is used as a monomer or a component in the production of polymers. Its aromatic structure may influence the properties of the resulting polymers, such as their strength, flexibility, or chemical resistance, making it a useful material in the development of new polymeric materials.
Note: As mentioned in the provided materials, 3-M-TOLYLOXY-PROPIONIC ACID has not been widely researched or used, and little information is available on its properties or potential applications. The uses listed above are speculative and based on the general properties of similar organic compounds. Further research is needed to confirm its specific properties and potential uses.

InChI:InChI=1/C10H12O3/c1-8-3-2-4-9(7-8)13-6-5-10(11)12/h2-4,7H,5-6H2,1H3,(H,11,12)/p-1

Upstream product

• 57-57-8 β-Propiolactone 
• 3019-89-4 sodium 3-methylphenoxide 
• 13030-21-2 3-(m-methylphenoxy)propan-1-ol 
• 25268-06-8 3-(m-tolyloxy)propionitrile. 
• 108-39-4 3-methyl-phenol 
• 107-13-1 acrylonitrile 
• 107-94-8 chloropropionic acid 
• 106-44-5 p-cresol 

Downstream Products

• 18385-69-8 7-methylchroman-4-one 
• 13629-89-5 3-m-Tolyloxy-propionsaeure-vinylester 
• 91634-24-1 3-<3-Carboxy-phenoxy>-propionsaeure 
• 91880-46-5 3-<3-Carbamoyl-phenoxy>-propionamid 
• 94112-90-0 3-<3-Aethoxycarbonyl-phenoxy>-propionsaeure-aethylester 
• 18385-68-7 5-methyl-2,3-dihydrochromen-4-one 
• 915923-06-7 C₁₁H₁₃N₃OS 
• 5751-51-9 7-methyl-4H-benzopyran-4-one 
• 90921-09-8 acide chromannone-4 carboxylique-7 

Relevant academic research and scientific papers

Acid activated montmorillonite K-10 mediated intramolecular acylation: Simple and convenient synthesis of 4-chromanones

3-Aryloxyproionic acids undergo intramolecular cyclization in the presence of AA.Mont.K-10 in toluene under reflux for 30–45 min in good to excellent yields. Phenyl ring bearing various substituents at the ortho, meta, para positions undergo this cyclization reaction. This method involves simple work up and amenable for large scale preparations. The heterogeneous acid treated catalyst can be regenerated and used for up to three cycles with minimum loss of activity.

Copper-Catalyzed Asymmetric Hydroboration of 2 H-Chromenes Using a Chiral Diphosphine Ligand

A highly regioselective asymmetric hydroboration of 2H-chromenes catalyzed by the complex of CuCl and diphosphine ligand (S,R)-DuanPhos has been realized under mild conditions to produce 3-boryl chromans, achieving good yields and excellent enantioselectivities up to 96% ee. This work provides an efficient approach to the synthesis of chiral 3-boryl chromans and derivatives.

Preparation method of oxygen heterocyclic compound

The invention discloses a preparation method of an oxygen heterocyclic compound 4-hydroxyl-5-methyl-3,4-dihydro-2H-chromene-4-carboxylic acid. With 4-methylphenol as a start raw material, a target product is prepared by condensation, ring closing, cyaniding, TMS removal and hydrolysis. The compound is an important pharmaceutical intermediate.

Synthesis, evaluation and in silico molecular modeling of pyrroyl-1,3,4-thiadiazole inhibitors of InhA

Enoyl acyl carrier protein reductase (ENR) is an essential type II fatty acid synthase (FAS-II) pathway enzyme that is an attractive target for designing novel antitubercular agents. Herein, we report sixty-eight novel pyrrolyl substituted aryloxy-1,3,4-thiadiazoles synthesized by three-step optimization processes. Three-dimensional quantitative structure-activity relationships (3D-QSAR) were established for pyrrolyl substituted aryloxy-1,3,4-thiadiazole series of InhA inhibitors using the comparative molecular field analysis (CoMFA). Docking analysis of the crystal structure of ENR performed by using Surflex-Dock in Sybyl-X 2.0 software indicates the occupation of pyrrolyl substituted aryloxy 1,3,4-thiadiazole into hydrophobic pocket of InhA enzyme. Based on docking and database alignment rules, two computational models were established to compare their statistical results. The analysis of 3D contour plots allowed us to investigate the effect of different substituent groups at different positions of the common scaffold. In vitro testing of ligands using biological assays substantiated the efficacy of ligands that were screened through in silico methods.

SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS

The present invention provides propyl phenoxy ether compounds and pharmaceutically acceptable salts thereof, compositions containing the same and one or more active agents, and methods of administering active agents with the same. The delivery agents of the present invention are well suited for forming non-covalent mixtures with active agents for oral, iπtracolonic, pulmonary, and other routes of administration to animals.

NOUVEAUX DERIVES DE LA BENZOPYRANNONE-4, A ACTIVITES ANALGESIQUE, ANTI-INFLAMMATOIRE ET ANTIAGREGANTE PLAQUETTAIRE

A series of 35 new derivatives of 3-benzylidene benzopyran-4-one carboxylic acid was synthesized; their antiinflammatory and analgesic activities were investigated and compared with those of acetylsalicylic acid, phenylbutazone, ketoprofene and glafenine.Among these compounds, four were found to be more potent than the references compounds in tests of antiinflammatory and analgesic activity.Seven compounds were tested on rat blood platelet aggregation induced by ADP.From these tests, HD-039, HD-041, HD-044 and HD-049 appear to be promising antiinflammatory, analgesic and anticlotting agents, although this original series shows little structural analogy with classical non-steroidal antiinflammatory agents.