25173-75-5 Usage
Uses
Used in Pharmaceutical Industry:
3-(2,5-DIMETHYLPHENYL)PROPIONIC ACID is used as a nonsteroidal anti-inflammatory drug (NSAID) for its ability to reduce inflammation and alleviate pain. It functions by inhibiting the production of prostaglandins, which are molecules that contribute to pain and inflammation within the body.
Used in Treatment of Various Conditions:
3-(2,5-DIMETHYLPHENYL)PROPIONIC ACID is used as a therapeutic agent for the treatment of conditions such as arthritis, menstrual cramps, and minor injuries. Its efficacy in these areas stems from its capacity to mitigate the symptoms associated with these health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 25173-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,1,7 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 25173-75:
(7*2)+(6*5)+(5*1)+(4*7)+(3*3)+(2*7)+(1*5)=105
105 % 10 = 5
So 25173-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14O2/c1-8-3-4-9(2)10(7-8)5-6-11(12)13/h3-4,7H,5-6H2,1-2H3,(H,12,13)
25173-75-5Relevant academic research and scientific papers
Iron-catalyzed, highly regioselective synthesis of α-aryl carboxylic acids from styrene derivatives and CO2
Greenhalgh, Mark D.,Thomas, Stephen P.
, p. 11900 - 11903 (2012/09/07)
The iron-catalyzed hydrocarboxylation of aryl alkenes has been developed using a highly active bench-stable iron(II) precatalyst to give α-aryl carboxylic acids in excellent yields and with near-perfect regioselectivity. Using just 1 mol % FeCl2, bis(imino)pyridine 6 (1 mol %), CO 2 (atmospheric pressure), and a hydride source (EtMgBr, 1.2 equiv), a range of sterically and electronically differentiated aryl alkenes were transformed to the corresponding α-aryl carboxylic acids (up to 96% isolated yield). The catalyst was found to be equally active with a loading of 0.1 mol %. Preliminary mechanistic investigations show that an iron-catalyzed hydrometalation is followed by transmetalation and reaction with the electrophile (CO2).
